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The importance of dyspnoea in the diagnosis of chronic obstructive pulmonary di...
Bárbara, C; Moita, J; Cardoso, J; Costa, R; Redondeiro, R; Gaspar, MINTRODUCTION: The aim of this study was to determine patient-perceived characteristics of chronic obstructive pulmonary disease (COPD) in patients participating in a large trial evaluating tiotropium bromide. PATIENTS AND METHODS: Baseline symptoms were assessed by means of a standardized questionnaire. Patients reported symptoms that led to diagnosis as well as their current most troublesome symptom. RESULTS: ...
A importância da dispneia no diagnóstico da doença pulmonar obstrutiva crónica:...
Bárbara, C; Moita, J; Cardoso, J; Costa, R; Redondeiro, R; Gaspar, MIntrodução: Este estudo teve como objectivo determinar os principais sintomas percepcionados pelos doentes com doença pulmonar obstrutiva crónica (DPOC) numa coorte de doentes que participaram num grande ensaio clínico, que avaliou o tiotrópio e que decorreu em Portugal. População e métodos: A caracterização dos sintomas, no momento de avaliação basal dos doentes foi efectuada através do recurso a um questionár...
A Importância da Dispneia no Diagnóstico da Doença Pulmonar Obstrutiva Crónica....
Bárbara, C; Moita, J; Cardoso, J; Costa, R; Redondeiro, R; Gaspar, MIntrodução: Este estudo teve como objectivo determinar os principais sintomas percepcionados pelos doentes com doença pulmonar obstrutiva crónica (DPOC) numa coorte de doentes que participaram num grande ensaio clínico, que avaliou o tiotrópio e que decorreu em Portugal. População e métodos: A caracterização dos sintomas, no momento de avaliação basal dos doentes foi efectuada através do recurso a um questionár...
Tiotropium improves FEV1 in patients with COPD irrespective of smoking status
Moita, J; Bárbara, C; Cardoso, J; Costa, R; Sousa, M; Ruiz, J; Santos, MLThis study evaluated whether the effect of tiotropium on the change in trough forced expiratory volume in 1s (FEV1), vs. placebo, is affected by smoking status. In a 3-month, double-blind study in 31 centres in Portugal, 311 (289 completed) patients were randomised to tiotropium 18 microg once daily or placebo. Baseline mean (standard deviation (SD)) FEV1 was 1.11 (0.39) l in the tiotropium group and 1.13 (0.39...
Acromegaly with the sleep apnea syndrome.
Ferreira, A M; Serviço de Psiquiatria, Hospitais da Universidade de Coimbra.; César, M H; Pissarra, C; dos Santos, F J; Moita, J; Coelho, IThe authors present the clinical of a male patient aged 45 years whose main complaints were loud snoring and excessive daytime sleepiness. Polysomnographic study revealed a sleep obstructive apnea syndrome with an apnea/hypopnea index of 86.5. After being treated with nasal continuous positive air pressure, (12 cm H2O), the apneas ended and sleep architecture was corrected. Physical examination also indicated t...
The effect of left ventricular dysfunction on nocturnal desaturation in patient...
dos Santos, J M; Serviço de Pneumologia, Centro Hospitalar de Coimbra.; Marques, A L; Moita, J; Pato, RThe possibility of nocturnal oxygen desaturation (NOD) in patients with chronic bronchitis and emphysema (CBE) even with basal hypoxemia greater that 55 mmHg is well recognised. Nocturnal hypoventilation is admitted as the main cause for this NOD. In this study we evaluate how the presence of left ventricular dysfunction (LVD) could aggravate NOD. Thirty-six patients with CBE and basal stabilised PaO2 55-70 mmH...
Collapse of the aortic valve in dilated myocardiopathies: echocardiographic stu...
Martins, R M; Morais, J; Isaac, J; Lopes, C; Correia, N F; Moita, J F; Monteiro, A A; Lopes, M RIn order to clarify the early systolic partial closure (notching) of aortic valve in patients (pts) with dilated cardiomyopathy (DC), authors (AA) evaluated the M-mode echocardiograms corresponding to 41 pts with DC. Pts were separated in two groups, according to the presence of systolic notching: group A (18 pts) presenting systolic notching; group B (23 pts) in which no systolic notching was observed. For eac...
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