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Microencapsulation and tissue engineering as an alternative treatment of diabetes
Maria-Engler,S.S.; Mares-Guia,M.; Correa,M.L.C.; Oliveira,E.M.C.; Aita,C.A.M.; Krogh,K.; Genzini,T.; Miranda,M.P.; Ribeiro,M.; Vilela,L.; Noronha,I.L.In the 70's, pancreatic islet transplantation arose as an attractive alternative to restore normoglycemia; however, the scarcity of donors and difficulties with allotransplants, even under immunosuppressive treatment, greatly hampered the use of this alternative. Several materials and devices have been developed to circumvent the problem of islet rejection by the recipient, but, so far, none has proved to be to...
The course of care for cancer patients hospitalized in a central hospital.
Miranda, M P; Serviço de Medicina I, Hospital Universitário de Santa Maria, Lisboa.; Oliveira, A; Coelho, M; Mendes, FPrevention and early diagnosis are considered the main tools to reduce the incidence and mortality from cancer. The authors studied prospectively 150 oncologic patients admitted to Santa Maria Hospital-Lisbon from April/92 to April/93, by personal interview, to analyze their assistance pathways from the appearance of first symptoms. We tried to define the role of the different medical assistance structures and ...
Essential thrombocythemia. Apropos a case of cerebrovascular stroke.
Oliveira, A S; Serviço de Medicina I, Hospital Universitário de Santa Maria, Lisboa.; Miranda, M P; Duarte, P C; Sarmento, J NThe authors report the case of a 60-year-old white man with a previous history of pulmonary tuberculosis, smoking habits, hypertension, intermittent claudication and erythromelalgia, admitted to our ward with an ischemic cerebral event. Initial laboratory evaluation documented thrombocytosis (platelet-950000/mm3) and discrete anemia. Additional studies confirmed the diagnosis of essential thrombocythemia, meeti...
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