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CYCLOTech - an innovative approach for the reliable production of 99mTc - techn...
Metello, Luís F.CYCLOTech is a high-tech Project, related with an innovative method for direct production of a radioactive pharmaceutical, used in excess of 85% of 35 Million Nuclear Medicine procedures done yearly, worldwide, representing globally more than 3 Billion Euros. The CYCLOTech team has developed an innovative proprietary methodology based on the use of Cyclotron Centers, formally identified as the Clients (actually...
Analysing the usefulness of motion correction software in myocardial perfusion ...
Cunha, Lídia; Lamego, Juliana; Ferreira, Sara; Lemos, Joana; Vieira, Domingos; Metello, Luís F.Introduction Myocardial Perfusion Imaging (MPI) is a very important tool in the assessment of Coronary Artery Disease ( CAD ) patient s and worldwide data demonstrate an increasingly wider use and clinical acceptance. Nevertheless, it is a complex process and it is quite vulnerable concerning the amount and type of possible artefacts, some of them affecting seriously the overall quality and the clinical utility...
Is there a need for attenuation correction in the 99mTc-DMSA scans on pediatric...
Nogueira, Fábio; Lemos, Joana; Oliveira, Marta; Silva, José A.; Sousa, Maria C.; Cunha, Lídia; Metello, Luís F.Introduction: The quantification of th e differential renal function in adults can be difficult due to many factors - on e of the se is the variances in kidney depth and the attenuation related with all the tissue s between the kidney and the camera. Some authors refer that t he lower attenuation i n p ediatric patients makes unnecessary the use of attenuation correction algorithms. This study will com pare the...
Evaluation of 99mTc-Sestamibi as a potential tool to investigate PgP activity i...
Costa, Pedro; Cunha, Lídia; Bravo, Joana; Alves, Cecília J.; Summavielle, Teresa; Metello, Luís F.Introduction: In the XXI Century ’s Society the scientific investigation process has been growing steadily , and the field of the pharmaceutical research is one of the most enthusiastic and relevant . Here, it is very important to correlate observed functional alterations with possibly modified drug bio distribution patterns . Cancer, inflammation and inf ection are processes that induce many molecular intermed...
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