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Preparação e caracterização de diferentes nanotransportadores sem substância ativa

Os nanotransportadores (NT) são sistemas desenvolvidos à escala nanométrica (< 1μm) sendo usados como veículo de substâncias ativas (SA) [1]. Atualmente a maioria dos trabalhos foca o encapsulamento de fármacos e caracterização dos NT obtidos, sendo escassos os dados relativos a NT sem SA. Este trabalho teve como objectivo a preparação e caracterização de diferentes tipos de NT sem SA: lipossomas (L), nanocápsu...

Perivascular-like cells contribute to the stability of the vascular network of ...

In recent years several studies have been supporting the existence of a close relationship in terms of function and progeny between Mesenchymal Stem Cells (MSCs) and Pericytes. This concept has opened new perspectives for the application of MSCs in Tissue Engineering (TE), with special interest for the pre-vascularization of cell dense constructs. In this work, cell sheet technology was used to create a scaffol...

Pericytes contribute to the stability of the vascular network of osteogenic tis...

Despite the increased use of cell sheets for tissue engineering, the appli- cation of this new technology for thick tissue reconstruction is being limited by old barriers such as the need to create a pre-vascular net- work to ensure proper nutrient and oxygen supply in vivo. In the pres- ent work, we created a cell sheet-based construct by co-culturing bone marrow-derived osteogenic and pericyte-like cells with...

Long-term melatonin treatment reduces ovarian mass and enhances tissue antioxid...

Melatonin regulates the reproductive cycle, energy metabolism and may also act as a potential antioxidant indoleamine. The present study was undertaken to investigate whether long-term melatonin treatment can induce reproductive alterations and if it can protect ovarian tissue against lipid peroxidation during ovulation. Twenty-four adult female Wistar rats, 60 days old (± 250-260 g), were randomly divided into...

Valores de Referência de Robustez Óssea: Avaliados Próximo ao Nascimento por Ul...

Objectivo: Estabelecer valores de referência da robustez óssea nos primeiros dias de vida, em recém-nascidos de termo e pré-termo adequados para a idade de gestação nascidos em Portugal. Métodos: Foi medida a velocidade do som (VdS) (m/s) por ultrassonografia quantitativa, numa amostra sistemática de recém-nascidos adequados para a idade de gestação, de termo e pré-termo, respectivamente nos primeiros dois e ci...

Ocorrência e caracterização molecular de Cryptosporidium em cordeiros

Soroprevalência de Maedi-Visna em ovinos na região de Araçatuba, SP

Non-Fluorinated Membranes Thickness Effect on the DMFC Performance

In order to study the influence of the proton exchange membrane thickness on the direct methanol fuel cell (DMFC) performance, sulfortated poly (ether ether ketone) (sPEEK) membranes with a sulfonation degree (SD) of 42% and thicknesses of 25, 40, and 55 pm were prepared, characterized, and tested in a DMFC. These polymeric membranes were tested in a DMFC at several temperatures by evaluating the current-voltag...

Estudo retrospectivo de 19 casos de polioencefalomalácia, em bovinos, responsiv...

Nineteen bovines of both sexes aging from 5 month-old to 5 year-old, were referred to a veterinary hospital. Clinical signs were observed from 6 hours to 10 days before. Thirteen animals were found in permanent lateral recumbency, five showed motor incoordination, 15 were exclusively fed on grass pasture, three showed partial loss of visual acuity, 14 were blindness, 16 showed presence of normal pupillary refle...

Avaliação dos reflexos espinhais em cordeiros da raça Suffolk

Fez-se a avaliação qualitativa e semiquantitativa dos reflexos espinhais em ovinos, utilizando-se 51 animais da raça Suffolk, machos e fêmeas, entre quatro e cinco meses de idade. Usaram-se os reflexos bilaterais dos membros torácicos, extensor carpo-radial, bicipital, tricipital e flexor, e pélvicos, isquiático, gastrocnêmio, patelar, tibial cranial e flexor, sendo zero indicativo de ausência de reflexo, 1= re...