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Diabetic Foot Infections: Current Diagnosis and Treatment
Mendes, JJ; Neves, JDiabetes mellitus (DM) is a global epidemic, and diabetic foot ulcer (DFU) is one of its most serious and costly complications. DFUs result from a complex interaction of a number of risk factors. Once the protective layer of skin is broken, deep tissues are exposed to bacterial infection that progresses rapidly. Patients with DFUs frequently require amputations of the lower limbs and, in more than half the case...
Clinical and Bacteriological Survey of Diabetic Foot Infections in Lisbon
Mendes, JJ; Marques-Costa, A; Vilela, C; Neves, J; Candeias, N; Cavaco-Silva, P; Melo-Cristino, JAIMS: An epidemiological survey of diabetic foot infections (DFIs) in Lisbon, stratifying the bacterial profile based on patient demographical data, diabetic foot characteristics (PEDIS classification), ulcer duration and antibiotic therapy. METHODS: A transversal observational multicenter study, with clinical data collection using a structured questionnaire and microbiological products (aspirates, biopsies or...
A Rat Model of Diabetic Wound Infection for the Evaluation of Topical Antimicro...
Mendes, JJ; Leandro, C; Bonaparte, D; Pinto, ADiabetes mellitus is an epidemic multisystemic chronic disease that frequently is complicated by complex wound infections. Innovative topical antimicrobial therapy agents are potentially useful for multimodal treatment of these infections. However, an appropriately standardized in vivo model is currently not available to facilitate the screening of these emerging products and their effect on wound healing. To d...
Miocardiopatia Não Compactada. Revisão a Propósito de Oito Casos
Toste, A; Branco, LM; Galrinho, A; Lousinha, A; Fiarresga, A; Oliveira, MM; Abreu, J; Mendes, JJ; Ferreira, ML; Leal, A; Cruz Ferreira, RA miocardiopatia não compactada isolada é uma doença geneticamente determinada cuja patogénese parece envolver uma paragem no desenvolvimento do endomiocárdio. Morfologicamente caracteriza-se pela presença de trabeculações proeminentes separadas por profundos recessos preenchidos por fluxo e como tal por Doppler a cor no estudo ecocardiográfico. No sentido de melhor caracterizar esta entidade recentemente descr...
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