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On the selectivity of Mycobacterium sp. NRRL B-3805 as steroid producer
Silva, Maria Cruz; Marques, Marco; Fernandes, Pedro; Melo, Maria Luísa Sá e; Cabral, Joaquimhttp://www.sciencedirect.com/science/article/B6T3C-4PB7582-7P/1/6704530c9694fd9eaf27304a215ae765
Data: 2007
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Origem: Estudo Geral - Universidade de Coimbra
Improved syntheses of aromatase inhibitors and neuroactive steroids efficient o...
Neves, André S. Campos; Melo, Maria Luisa Sá e; Moreno, Maria José S. M.; Silva, Elisiário J. Tavares da; Salvador, Jorge A. R.; Costa, Saul P. daAn Henbest reduction, followed by the preparation of a silyl enol ether and oxidation in situ with m-CPBA has led to the neurosteroids 3[alpha]-hydroxy- and 3[alpha],21-dihydroxy-5[alpha]-pregnanolones. Using testosterone as starting material, a new short synthesis of an aromatase inhibitor, 4-OHA, has been achieved through hydroboration/oxidation followed by a Swern type oxidation and epimerization. Another ar...
Data: 1999
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Origem: Estudo Geral - Universidade de Coimbra
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