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Involvement of oxidative stress in the enhancement of acetylcholinesterase acti...
Melo, Joana Barbosa; Agostinho, Paula; Oliveira, Catarina ResendeAcetylcholinesterase (AChE) activity is increased within and around amyloid plaques, which are present in Alzheimer's disease (AD) patient's brain. In this study, using cultured retinal cells as a neuronal model, we analyzed the effect of the synthetic peptide A[beta]25-35 on the activity of AChE, the degradation enzyme of acetylcholine, as well as the involvement of oxidative stress in this process. The activi...
Data: 2003
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Origem: Estudo Geral - Universidade de Coimbra
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