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The deformation of cylindrical shells subjected to radial loads using mixed for...

The objective of this work is to contribute with a simple and reliable numerical tool for the stress analysis of cylindrical vessels subjected to generalized forces using a mixed formulation. Variational techniques coupled with functional analysis are used to obtain an optimized solution for the shell displacement and further stress field evaluation using a combination of unknown analytic functions with Fourier...

Pediatria do neurodesenvolvimento: levantamente nacional de recursos e necessid...

Sitagliptin delays progression of renal lesions in a rodent model of type 2 dia...

Pediatria do Neurodesenvolvimento. Levantamento Nacional de Recursos e Necessid...

As perturbações do neurodesenvolvimento são das patologias crónicas mais frequentes da infância e com tendência a aumentar nas sociedades modernas. Têm na grande maioria dos casos um percurso crónico e com limitação da aprendizagem necessária para a integração na sociedade de um modo autónomo. A Sociedade de Pediatria do Neurodesenvolvimento da Sociedade Portuguesa de Pediatria procedeu em 2008 e 2009 ao levant...

Exercise Can Improve Speed of Behavior in Older Drivers

The main aim of this research was to study the effects of a specific exercise program on the speed of behavior of older adults during on-the-road driving. Twenty-six drivers (55–78 yr old) were randomly assigned to either an exercise group or a control group. The exercise program (3 sessions of 60 min/wk for 8 wk) incorporated tasks that induced the participants to respond quickly to challenging situations. On-...

Pancreatic lesions and metabolic aggravation are prevented by low doses of sita...

Introduction: The management of type 2 diabetes is designed to reduce disease-related complications and improve long-term outcomes. Inhibition of dipeptidyl peptidase-4 (DPP-4) activity by sitagliptin has been shown to improve glycaemic control in patients with type 2 diabetes Mellitus (T2DM) by prolonging the actions of incretin hormones, but the real impact of low-dose sitagliptin treatment on cardiometabolic...

Renal structure modification in an animal model of type 2 diabetes with aging: ...

Background and aims: The Zucker Diabetic Fatty (ZDF-fa/fa) rat is one of the most used models for the study of type 2 diabetes (T2DM). Characterization of renal morphology in this model may provide useful insights into the mechanism of diabetic nephropathy progression. The purpose of the present study was to determine renal morphology, identify and characterize renal dysfunction complications such as hydronephr...

A multi-nodal ring finite element for analysis of pipe deflection

The main objective of this work is to present a numerical formulation to solve the problem of the deformation analysis ot thin-walled circular cylindrical pipes under concentred loads. The solutions is based on a displacement field entirely defined from a set of trigonometic functiobns where the amplitudes are assigned as a nodal paramenters in a multi-nodal finite element. With this formulation it is possible ...

Polarized Raman spectra of L-arginine hydrochloride monohydrated single crystal

Polarized Raman spectra of L-arginine hydrochloride monohydrated single crystal in nine different scattering geometries of the two irreducible representations of factor group C2 were studied at room temperature. The experimental wavenumber values are compared with those obtained from ab-initio calculation and the assignment of the Raman bands to the respective molecular vibrations is also given. Finally, a disc...

Numerical solution of curved pipes submitted to in-plane loading conditions

An alternative formulation to current meshes dealing with finite shell elements is presented to solve the problem of stress analysis of curved pipes subjected to in-plane bending forces. The solution is based on finite curved elements, where displacements are defined from a total set of trigonometric functions or a fifth-order polynomial, combined with Fourier series. Global shell displacements are achieved thr...