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Silk fibroin microparticles as carriers for delivery of human recombinant bone ...
Bessa, Paulo C.; Balmayor, Elizabeth Rosado; Hartinger, Joachim; Zanoni, Gerald; Dopler, Daniela; Meinl, Alexandra; Banerjee, Asmita; Casal, MargaridaThe in vitro and in vivo efficiency of fibroin microparticles as a delivery carrier for bone morphogenetic protein-2 (BMP-2) was evaluated. BMP-2 was encapsulated in silk fibroin particles that were produced by a simple and very mild processing method. The dose-response of BMP-2-loaded fibroin particles was examined in C2C12 cells, after 5 days of culture. The BMP-2 retained most of its activity as observed by ...
Data: 2010
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Origem: RepositóriUM - Universidade do Minho
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