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Profile of antimicrobial potential of fifteen Hypericum species from Portugal
Nogueira, Teresa; Medeiros, Maria Augusta; Curto, Maria João Marcelo; Garcia-Pérez, B. E.; Luna-Herrera, J.; Costa, Maria do CéuThe aim of the present study was the search for the industrial exploitation potential of 15 Hypericum species crops from Portugal. Although Hypericum perforatum is well known worldwide, scarce studies have been published of Hypericum spp. identified in Portugal. Extracts from 15 Hypericum species were screened for its antimicrobial activities against 2 Gram- and 2 Gram+ bacteria, 4 non-tuberculous Mycobacterium...
Pharmacological characterization of Solanum cernuum Vell.: 31-norcycloartanones...
Lopes, Luciane C.; Carvalho, João E.; Kakimore, Marise; Vendramini-Costa, Débora B.; Medeiros, Maria Augusta; Spindola, Humberto M.; Ávila-Román, J.Cycloeucalenone (1) and 24-oxo-31-norcycloartanone (2) obtained from Solanum cernuum Vell. were assayed to explore their pharmacologic roles. Previous studies showed that (2) has selective activity against lung tumor cell line (NCIH460) which expresses high levels of COX-2, suggesting its role in inflammatory process, and also a link between chronic inflammation and cancer-associated process. Dichloromethane cr...
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