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Maxilla osseus sequestre and oral exposure: effects of the treatment of multipl...

Lobato, J V; Rodrigues, J M; Cavaleiro, M V; Lobato, J M; Xavier, L; Santos, J D; Maurício, Ana C

Multiple myeloma, the second most common haematopoietic cancer, represents a collection of plasma-cell neoplasms that invariably become fatal when self-renewing myeloma cells begin unrestrained proliferation. The major clinical manifestation of multiple myeloma is related to loss of bone through osteolysis. The bone disease can lead to pathologic fractures, spinal cord compression, hypercalcemia, and pain. It i...

Data: 2007   |   Origem: Acta Médica Portuguesa

Ionic transport in tall columnar epithelial (TCE) cells obtained by nasal brush...

Maurício, Ana C; Penque, D; Amaral, M D; Ferreira, K T

Tall columnar epithelial (TCE) cells can be obtained by a non-invasive procedure through brushing the inferior turbinate and the adjacent lateral nasal wall. Here, we present results from the functional study of epithelial cells, thus obtained by using the patch-clamp technique. By patch-clamping the sub-apical region of TCE cells, we were able to identify at least three different groups of Cl- channels, namely...

Data: 2004   |   Origem: Acta Médica Portuguesa

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia