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Development of a new application of the comet assay to assess levels of O6-meth...

O6-methylguanine (O6meG) is one of the most premutagenic, precarcinogenic, and precytotoxic DNA lesions formed by alkylating agents. Repair of this DNA damage is achieved by the protein MGMT, which transfers the alkyl groups from the O6 position of guanine to a cysteine residue in its active center. Because O6meG repair by MGMT is a stoichiometric reaction that irreversibly inactivates MGMT, which is subsequent...

Sap flow scaling and crop coefficient of dry-farmed olive orchards converted to...

Tree water uptake is often estimated based in a crop coefficient kc, a ratio of the tree water uptake and a reference evapotranspiration, ET0. The concept behind estimating tree crop coefficient implies that data should be representative of the population of trees analyzed. Ideally it would require the monitoring of a large number of trees in each treatment population. This paper reports on a scaling method to ...

Diet supplemented with UA or EGCG confer protection against DNA damage in colon...

Diet is an important factor in colorectal cancer. High fat diets are considered a risk factor for the development of colon cancer as they increase the content of bile acids in the colon. Bile acids have shown to induce the formation of reactive oxygen and nitrogen species, and these, in turn, induce DNA damage. On the other hand, diets rich in fruits and vegetables have shown preventive effects on colon cancer....

Diet and DNA damage : in vivo effects of dietary compounds on isolated colonocy...

TRANSPIRATION AND CROP COEFFICIENTS FOR IRRIGATED OLIVES WITH PREDICTIVE EQUATI...

Olive transpiration T can be predicted by combining MODIS remotely sensed vegetation indices (EVI* and NDVI*), tree ground-based transpiration derived from sap flow measurements and maximum daily air temperature ta. The feasibility of developing a single predictive equation of olive orchard transpiration through the relationship between sap flow based transpiration (T) and remotely sensed Enhanced and Normalize...

Human values and opposition towards immigration in Europe

Tese de doutoramento, Ciências Sociais (Sociologia Geral), Universidade de Lisboa, Instituto de Ciências Sociais, 2011 ; Three main objectives underlie this thesis: 1) understand opposition towards immigration in Europe; 2) test the hypothesis that human values contribute to the understanding of opposition towards immigration over and above other social factors; 3) undertake this analysis from a multilevel per...

DNA damage protection and induction of repair by dietary phytochemicals and can...

Diet and colon cancer - modulation of signaling pathways and DNA damage prevention

Colorectal cancer (CRC) is a common malignancy and significant cause of death in Western societies. It develops through an accumulation of genetic and epigenetic alterations, transforming normal cells and giving them growth advantage. Many food plants are rich in bioactive compounds and have shown to posses anticancer properties. We proposed to explore the effects of sage (Salvia officinalis (SO)) water extract...

DNA damage prevention and signaling pathway regulation by sage in a colon cance...

Colorectal cancer (CRC) is a common malignancy and significant cause of mortality in Western societies. It develops through an accumulation of genetic and epigenetic alterations, transforming normal colon cells and giving them growth advantage. Many food plants are rich in bioactive compounds and have shown to posses anticancer properties. We proposed to explore the effects of sage (Salvia officinalis (SO)) wat...