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A brief summary of the progress on the EFDA tungsten materials program
Rieth, M.; Dudarev, S. L.; Vicente, S. M. Gonzalez de; Aktaa, J.; Ahlgren, T.; Antusch, S.; Armstrong, D. E. J.; Balden, M.; Baluc, N.; Barthe, M. F.The long-term objective of the European Fusion Development Agreement (EFDA) fusion materials programme is to develop structural and armor materials in combination with the necessary production and fabrication technologies for reactor concepts beyond the International Thermonuclear Experimental Reactor. The programmatic roadmap is structured into four engineering research lines which comprise fabrication process...
Differentiation of mesenchymal stem cells in chitosan scaffolds with double mic...
Garcia Cruz, Dunia M.; Gomes, Manuela E.; Reis, R. L.; Moratal, David; Salmerón-Sánchez, M.; Gómez Ribelles, J. L.; Mano, J. F.Bone Marrow mesenchymal stem cells can be induced to differentiate into osteoblasts to regenerate damaged bone tissue using tissue engineering techniques. In this study, we examine the use of chitosan scaffolds with double pore structure prepared by an innovative method that combines freeze gelation (that produces micropores) and particle leaching out technique (that produces interconnected spherical macropores...
Proliferation and differentiation of goat bone marrow stromal cells in 3d scaff...
Escobar Ivirico, J. L.; Salmerón-Sánchez, M.; Gómez Ribelles, J. L.; Monleón Pradas, M.; Soria, Jose Miguel; Gomes, Manuela E.; Reis, R. L.; Mano, J. F.We have synthesized methacrylate-endcapped caprolactone networks with tailored water sorption ability, poly(CLMA-co-HEA), in the form of three-dimensional (3D) scaffolds with the same architecture but exhibiting different hydrophilicity character (xHEA50, 0.3, 0.5), and we investigated the interaction of goat bone marrow stromal cells (GBMSCs) with such structures. For this purpose, GBMSCs were seeded and cultu...
Chitosan microparticles as injectable scaffolds for tissue engineering
Garcia Cruz, Dunia M.; Escobar Ivirico, J. L.; Gomes, Manuela M.; Gómez Ribelles, J. L.; Salmerón-Sánchez, M.; Reis, R. L.; Mano, J. F.The use of chitosan microparticles as injectable carriers for cell transplantation represents a promising alternative to avoid the drawbacks of the implantation of other forms of three-dimensional (3D) scaffolds seeded with cells. In this study, a 3D construct is obtained in vitro by combining chitosan microparticles crosslinked with genipin and goat bone marrow stromal cells (GBMCs). Cell viability and the mor...
Impressões sobre o teste rápido para o HIV entre usuários de drogas injetáveis ...
Telles-Dias,PR; Westman,S; Fernandez,AE; Sanchez,MOBJETIVO: Descrever as impressões, experiências, conhecimentos, crenças e a receptividade de usuários de drogas injetáveis para participar das estratégias de testagem rápida para HIV. MÉTODOS: Estudo qualitativo exploratório foi conduzido entre usuários de drogas injetáveis, de dezembro de 2003 a fevereiro de 2004, em cinco cidades brasileiras, localizadas em quatro regiões do País. Um roteiro de entrevista sem...
Glass transition dynamics and structural relaxation of PLLA studied by DSC : In...
Mano, J. F.; Gómez Ribelles, J. L.; Alves, N. M.; Salmerón-Sánchez, M.Poly(L-lactic acid), PLLA, in amorphous and semi-crystalline forms were studied by DSC, in order to investigate both molecular dynamics and structural relaxation features, and to understand the influence of the crystalline confinement on the segmental mobility of the intraspherulitic amorphous phase. Experimental data were generated after submitting the materials to different thermal histories below Tg and were...
Vitamin content of fish and fish products consumed in Portugal
Dias, M. Graça; Sánchez, M V; Bártolo, H; Oliveira, LuísaPortuguese Food Composition Table only includes values for vitamins A, B1, B2, PP determined before 1963. Most fish and fish products consumed in Portugal are not included in international food composition tables. Aims: To study vitamin content of fish and fish products consumed in Portugal. Design: Vitamins A, E, D, B1, B2, B6, B12, PP and Folate content was determined in fifty-six samples of raw and cooked fi...
Non-conventional yeasts as hosts for heterologous protein production.
Domínguez, A.; Fermiñán, E.; Sánchez, M.; Gonzalez, Francisco M.; Pérez-Campo, F. M.; García, S.; Herrero, A.B.; San Vicente, A.; Cabello, J.; Prado, M.Yeasts are an attractive group of lower eukaryotic microorganisms, some of which are used in several industrial processes that include brewing, baking and the production of a variety of biochemical compounds. More recently, yeasts have been developed as host organisms for the production of foreign (heterologous) proteins. Saccharomyces cerevisiae has usually been the yeast of choice, but an increasing number of...
Enzymic Determination of Primary Normal Alcohols as Apparent Ethanol Content in...
Huidobro, José F.; Rea, M. Estrella; Andrade, Paula C. Branquinho de; Sanchez, M. P.; Sancho, M. Teresa; Muniategui, Soledad; Simal-Lozano, JesúsPrimary normal alcohols of 33 unpasteurized Galician (northwestern Spain) honeys have been determined as apparent ethanol contents. A modification of the Boehringer-Mannheim enzymatic method has been used. The solution of honey has been employed directly, neither clarified nor neutralized. Removal of interferences required absorbance measurements at 340 nm, by using the solution of honey with the solution of al...
Secondary stroke prevention.
Ferro, J M; Serviço de Neurologia, Hospital de Santa Maria/Faculdade de Medicina de Lisboa.; Correia, M; Freire, A; Perez y Sanchez, J; Abrunhosa, M AThe guidelines for secondary stroke prevention, graded following available scientific evidence, are presented. Stroke and TIA are defined and the indications for referral established. Basic assessment of stroke patients should include laboratory evaluation, ECG, brain CT, ultrasound examination of the extracranial vessels for events in the carotid distribution, and transthoracic or transesophageal echocardiogra...
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