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Crosstalk between genetics, gene expression and biochemical markers supports sy...

Iron Related Gene Expression and Biochemical Phenotype Support Iron Homeostasis...

Sonochemical and hydrodynamic cavitation reactors for laccase/hydrogen peroxide...

Article in press ; The main goal of this work is to develop a novel and environmental-friendly technology for cotton bleaching with reduced processing costs. This work exploits a combined laccase–hydrogen peroxide process assisted by ultrasound. For this purpose, specific reactors were studied, namely ultrasonic power generator type K8 (850 kHz) and ultrasonic bath equipment Ultrasonic cleaner USC600TH (45 kHz...

Iron/copper metabolism in Alzheimer’s disease: genetics and biomarkers in a Por...

This work was supported by Fundação Astrazeneca through the “Programa de Apoio à Investigação” . Presented at the “International Conference in Alzheimer’s Disease 2009 ; The distinction between normal aging and Alzheimer's disease (AD) is a relevant step to combat this disease efficiently. Thus, the identification of biomarkers and genetic factors underlying AD pathology is extremely important. Oxidative injur...

Molecular recognition of esterase plays a major role on the removal of fatty so...

In this work it is describe for the first time, the use of an esterase with null activity (Tfu_0883 bacterial cutinase from Thermobifida fusca) on the removal of fat from the surface of a cotton substrate. Similar levels of fat removal were found for both null and wild-type proteins, despite that only wild type protein yielded fatty acids. Our results show that molecular recognition of esterase plays a major ro...

Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the d...

Abstract Autism is a neurodevelopmental disorder of unclear etiology. The consistent finding of platelet hyperserotonemia in a proportion of patients and its heritability within affected families suggest that genes involved in the serotonin system play a role in this disorder. The role in autism etiology of seven candidate genes in the serotonin metabolic and neurotransmission pathways and mapping to autism li...

Experimental model for endometriosis. Comparative histological study between th...

Thyrty-six rats werw implanted with endometrial squares (2 X 2mm) to the left parietal peritoneum and the right uterine horn was tied. The rats were mated for 20 days and then sacrificed. Topic and ectopic endometrial histological pattern were compared. There was a correlation between the histological pattern of the autografted endometrium and the eutopic endometrium im most rats, pregnant or not. This suggests...