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Synthesis and Biological Activity of 6-Selenocaffeine: Potential Modulator of C...
Martins, I. L.; Miranda, J. P.; Oliveira, N. G.; Fernandes, A. S.; Gonçalves, S.; Antunes, A. M.We report the development of a new microwave-based synthetic methodology mediated by Woollins’ reagent that allowed an efficient conversion of caffeine into 6-selenocaffeine. A preliminary evaluation on the modulation of antioxidant activity upon selenation of caffeine, using the DPPH assay, indicated a mild antioxidant activity for 6-selenocaffeine, contrasting with caffeine, that exhibited no antioxidant acti...
Data: 2013
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Origem: ReCiL - Repositório Científico Lusófona
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