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The involvement of CDH1 in cancer angiogenesis

Dissertação para obtenção do Grau de Mestre em Biotecnologia ; Cancer is one of the leading causes of death worldwide. Biological hallmarks such as induced and sustained angiogenesis are implicated in tumour progression, as well as invasion and metastasis which are the major causes of cancer-related mortality. E-Cadherin impairment on the cell membrane is intimately related with invasion and metastasis. Also, ...