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Desenvolvimento de metodologias analíticas para a determinação de metadona, bup...

Mariano, Anabela Cardoso

Throughout human history, almost all countries and cultures contacted situations of use and abuse. Since the drugs have always been used for several reasons among which may highlight religious reasons, medical reasons and reasons related to recreation and fun. Today the question of drug associates a wide variety of social and economic problems of which we highlight the crime, violence and neglect of family life...


Resveratrol affords protection against peroxynitrite-mediated endothelial cell ...

Brito, Paula M.; Mariano, Anabela; Almeida, Leonor M.; Dinis, Teresa C. P.

Atherosclerosis, the main cause of cardiovascular disease (CD), is a chronic inflammatory condition associated with an overproduction of oxidant species, namely peroxynitrite, which is a powerful oxidant that reacts directly with all biomolecules. Glutathione is an efficient scavenger of peroxynitrite, so, modulation of glutathione synthesis may provide a strategy to selectively protect cells from this oxidant....


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia