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Translational control of the human hemojuvelin via upstream open reading frames
Onofre, Claudia; Barbosa, Cristina; Romão, LuísaIron is an essential element for many biological reactions carried out by living systems. A tight regulation of systemic iron homeostasis is crucial to avoid the pathological conditions of iron deficiency or overload. Juvenile hemochromatosis, is an early-onset inherited disorder associated to iron overload caused by mutations on the hepcidin gene or in the gene encoding hemojuvelin (HJV). HJV is a glycosylphos...
Gene expression regulation of human hemojuvelin by two small open reading frames
Onofre, Cláudia Alexandra da Silva, 1989-Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2012 ; The iron is an essential element for many biological reactions carried out by living systems. A tight regulation of the systemic iron homeostasis is crucial to avoid pathological conditions of iron deficiency or overload. Juvenile Hemochromatosis is an early-onset inherited disorder associated to an i...
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