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Heterogeneity in susceptibility to infection can explain high reinfection rates

Rodrigues, P.; Margheri, A.; Rebelo, C.; Gomes, M.G.M.

Heterogeneity in susceptibility and infectivity is inherent to infectious disease transmission in nature. Here we are concerned with the formulation of mathematical models that capture the essence of heterogeneity while keeping a simple structure suitable of analytical treatment. We explore the consequences of host heterogeneity in the susceptibility to infection for epidemiological models for which immunity co...


Dynamical behaviour of epidemiological models with sub-optimal immunity and non...

Gomes, M. G. M.; Margheri, A.; Medley, G. F.; Rebelo, C.

In this paper we analyze the dynamics of two families of epidemiological models which correspond to transitions from the SIR (susceptible-infectious-resistant) to the SIS (susceptible-infectious-susceptible) frameworks. In these models we assume that the force of infection is a nonlinear function of density of infectious individuals, I. Conditions for the existence of backwards bifurcations, oscillations and Bo...


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