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Duration of Antibiotic Therapy in Bacterial Meningitis
Pereira, P Ricardo; Serviço de Medicina Interna. Hospital Pedro Hispano. Matosinhos, Portugal.The duration of antibiotic therapy in bacterial meningitis is a controversial issue. Antibiotic regimens have changed over time along with the criteria used to determine the ideal antibiotic therapy duration. The authors aim to make an historical overview on this matter and simultaneously add the evidence of recent studies, pointing out some issues in results interpretation, namely, their design and the associa...
Cardiovascular risk in HIV infected patients.
Raimundo, Pedro; Miranda, A; Ribeiro, J; Mansinho, KamalThe increased cardiovascular risk has been implicated in both HIV infection and antirretroviral therapy. The endothelial dysfunction triggered by the infection and the metabolic abnormalities associated with therapy predispose to premature atherosclerosis. The recognition of the increased cardiovascular risk in these patients will allow more appropriate prevention strategies, as well as therapy optimization wit...
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