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Occupational exposure to aflatoxin (AFB1) in poultry production

Viegas, Susana; Veiga, Luísa; Malta-Vacas, Joana; Sabino, Raquel; Figueiredo, Paula; Almeida, Ana; Viegas, Carla

Aflatoxin B1 (AFB1) has been recognized to cause cancer in the humans liver. Epidemiological and laboratory evidence also point towards the respiratory system as target for carcinogenesis. Exposure occurs mainly through food chain but inhalation represent an additional route of exposure. Agricultural workers have the greatest risk of occupational exposure due to their exposition to airborne aflatoxin through in...


Fungal contamination of poultries litter: a public health problem

Viegas, Carla; Carolino, Elisabete; Malta-Vacas, Joana; Sabino, Raquel; Viegas, Susana; Veríssimo, Cristina

Exposure to certain fungi can cause human illness. Fungi cause adverse human health effects through three specific mechanisms: generation of a harmful immune response (e.g., allergy or hypersensitivity pneumonitis); direct infection by the fungal organism; by toxic-irritant effects from mold byproducts, such as mycotoxins. In Portugal there is an increasingly industry of large facilities that produce whole chic...


Exposure to microbial volatile organic compounds in a waste-handling unit

Viegas, Susana; Malta-Vacas, Joana; Viegas, Carla

The production of MVOC by fungi has been taken into account especially from the viewpoint of indoor pollution with microorganisms but the relevance of fungal metabolites in working environments has not been sufficiently studied. The purpose of this study was to assess exposure to MVOCs in a waste-handling unit. It was used Multirae equipment (RAE Systems) to measured MVOCs concentration with a 10.6 eV lamps. Th...


Occupational exposure to toxigenic fungi from Aspergillus flavus complex

Malta-Vacas, Joana; Sabino, Raquel; Viegas, Susana; Viegas, Carla

Bioaerosols are mainly composed of fungal particles, bacteria and plant spores, being fungi responsible for the release of VOCs and micotoxins into indoor environments. Aspergillus flavus is a common opportunistic pathogen causing human infections and is involved in the production of aflatoxin and other secondary metabolites associated with toxic and allergic reactions. Poultry workers are exposed to high conce...


Fast growing fungi: a problem to be solved to achieve characterization of occup...

Nunes, Ana Carolina; Domingues, A.; Malta-Vacas, Joana; Viegas, Carla

Chrysonilia sitophila is a common mould in cork industry and has been identified as a cause of IgE sensitization and occupational asthma. This fungal species have a fast growth rate that may inhibit others species’ growth causing underestimated data from characterization of occupational fungal exposure. Aiming to ascertain occupational exposure to fungi in cork industry, were analyzed papers from 2000 about the...


Micronuclei in peripheral blood lymphocytes in formaldehyde occupationally expo...

Ladeira, Carina; Viegas, Susana; Prista, João; Malta-Vacas, Joana; Gomes, Mário; Mendonça, Paula; Brito, Miguel

Formaldehyde (CH2O) the most simple and reactive of all aldehydes, is a colorless, reactive and readily polymerizing gas at normal temperature. It has a pungent, suffocating odour that is recognized by most human subjects at concentrations below 1 ppm. According to the Report on Carcinogens, formaldehyde (FA) ranks 25th in the overall U.S. chemical production with more than 11 billion pounds (5 million tons) pr...


Genotoxic effects in occupational exposure to formaldehyde: A study in anatomy ...

Viegas, Susana; Ladeira, Carina; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mário; Brito, Miguel; Mendonça, Paula; Prista, João

Background - According to the Report on Carcinogens, formaldehyde ranks 25th in the overall U.S. chemical production, with more than 5 million tons produced each year. Given its economic importance and widespread use, many people are exposed to formaldehyde environmentally and/or occupationally. Presently, the International Agency for Research on Cancer classifies formaldehyde as carcinogenic to humans (Group 1...


Gene expression regulation and lineage evolution: the North and South tale of t...

Pala, Irene; Schartl, Manfred; Brito, Miguel; Malta-Vacas, Joana; Coelho, Maria Manuela

The evolution of hybrid polyploid vertebrates, their viability and their perpetuation over evolutionary time have always been questions of great interest. However, little is known about the impact of hybridization and polyploidization on the regulatory networks that guarantee the appropriate quantitative and qualitative gene expression programme. The Squalius alburnoides complex of hybrid fish is an attractive ...


Occupational exposure to formaldehyde in anatomy and pathology laboratories: di...

Viegas, Susana; Ladeira, Carina; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mário; Brito, Miguel; Mendonça, Paula; Prista, João

Formaldehyde, also known as formalin, formal and methyl aldehydes, is a colorless, flammable, strong-smelling gas. It has an important application in embalming tissues and that result in exposures for workers in the pathology anatomy laboratories and mortuaries. To perform exposure assessment is necessary define exposure groups and in this occupational setting the technicians and pathologists are the most impor...


Occupational exposure to formaldehyde: effects of years of exposure in the freq...

Ladeira, Carina; Viegas, Susana; Nunes, Carla; Malta-Vacas, Joana; Gomes, Mário; Mendonça, Paula; Prista, João; Gomes, Manuel C.; Brito, Miguel

Formaldehyde: an important industrial compound used in the manufacture of synthetic resins and chemical compounds such as lubricants and adhesives; also applied as a disinfectant, preservative and in cosmetics productions; relevant workplace exposure to FA also occurs in anatomy, pathology and in mortuaries; classified by IARC as carcinogenic to humans (Group 1), based on sufficient evidence in humans and exper...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia