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Discovering and exploiting bacterial proteins as anticancer agents

Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2013 ; Azurin is a low molecular weight protein, produced by Pseudomonas aeruginosa and possesses several antitumor properties, like causing P-cadherin levels to decrease in invasive breast cancer cells. In this work, we studied the effect of lysosome and proteasome inhibitors on P-cadherin level, using a br...