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Motor-Independent Targeting of CLASPs to Kinetochores by CENP-E Promotes Microt...
Maffin, Stefano; Maia, Ana R. R.; Manning, Amity L.; Maliga, Zoltan; Pereira, Ana L.; Junqueira, Magno; Shevchenko, Andrej; Hyman, AnthonyEfficient chromosome segregation during mitosis relies on the coordinated activity of molecular motors with proteins that regulate kinetochore attachments to dynamic spindle microtubules [1]. CLASPs are conserved kinetochore- and microtubule-associated proteins encoded by two paralogue genes, clasp1 and clasp2, and have been previously implicated in the regulation of kinetochore-microtubule dynamics [2-4]. Howe...
Data: 2009
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Origem: Repositório Aberto da Universidade do Porto
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