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General model for delayed feedback and its application to transimpedance amplif...
Alves, L. N.; Barbosa, L.; Macedo, E.A.L.; Aguiar, R.L.Delays in real systems can be of two types: i) intrinsic delays - due to the physical principles of operation of each electronic device; ii) designed delays - due to extra circuits used to add the desired delay. Previous work established the possibility of achieving bandwidth improvements using small delays inside the feedback loop of feedback amplifiers. The modeling approach followed on these contributions us...
Lysozyme and bovine serum albumin partitioning in polyethylene glycol–phenylala...
Silvério, Sara C.; Ferreira, Luísa A.; Martins, J. A.; Marcos, João Carlos; Macedo, E. A.; Teixeira, J. A.Polyethylene glycol (PEG) with average molecular weight of 8000 was used as a model polymer and modified by introducing an amino acid (phenylalanine) in its hydroxyl terminals. The effect of different percentages of the conjugate polymer in relation to the total polymer on binodal curve of PEG-8000–potassium phosphate buffer (KPB), pH 7.2 aqueous two-phase systems and solute partitioning was explored. The parti...
(Liquid + liquid) equilibria of polymer-salt aqueous two-phase systems for lacc...
Lladosa, Estela; Silvério, Sara C.; Rodríguez, Oscar; Teixeira, J. A.; Macedo, E. A.Aqueous two-phase systems (ATPS) are recognized as very suitable techniques for the recovery of target solutes in biological applications. Three new phase diagrams of (UCON 50-HB-5100 + potassium citrate + water), (UCON 50-HB-5100 + sodium formate + water), and (UCON 50-HB-5100 + potassium formate + water) systems were measured at 23 C. The binodal curves were successfully described using the empirical equation...
Solubility of drug-like molecules in pure, mixed and supercritical solvent syst...
Mota, F.L.; Queimada, A.J.; Pinho, Simão; Macedo, E.A.Most of the active pharmaceutical ingredients (API) are purified by crystallization being solubility a key property, and it also affects their efficacy, release, transport and absorption in the organism [1]. Although of extreme importance, data involving druglike molecules are still scarce. In recent years, efforts have been made towards the development of predictive tools to calculate phase behaviour of the AP...
Liquid-liquid equilibrium of water +1-butanol + amino acid (glycine or DL-alani...
Santos, G.R.; Souza, D.C.; Aznar, M.; Pinho, Simão; Macedo, E.A.Amino acid play an important role both in animal metabolism and in industrial processes. Since they are rarely found in nature in free form, they must be obtained form hydrolisis of protein-containing materials, or by fermentation. These production methods often results in aqueouse mixtures containing various solutes included several types of amino acids. As a consequence, the cost of the separation processses ...
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