The conformational preferences of a series of hydroxylated isoflavones were studied by optical vibrational spectroscopy (FTIR and Raman) coupled with density functional theory (DFT) calculations. Special attention was paid to the effect of the hydroxyl substitution, due to the importance of this group in the biological activity of these systems. The isoflavones investigated – daidzein, genistein and formononeti...
Background Intermittent hypobaric-hypoxia (IHH) and endurance-training (ET) are cardioprotective strategies against stress-stimuli. Mitochondrial modulation appears to be an important step of the process. This study aimed to analyze whether a combination of these approaches provides additive or synergistic effects improving heart-mitochondrial and cardiac-function. Methods Two-sets of rats were divided into no...
The conformational preferences of a series of hydroxylated isoflavones were studied by optical vibrational spectroscopy (FTIR and Raman) coupled with density functional theory (DFT) calculations. Special attention was paid to the effect of the hydroxyl substitution, due to the importance of this group in the biological activity of these systems. The isoflavones investigated – daidzein, genistein and formononeti...
The solution Raman pattern of a series of structurally related hydroxycinnamic and hydroxybenzoicesters (caffeates and gallates) with potential antioxidant/anticancer activity was studied, for different biologically significant concentrations. The spectra were assigned with the help of theoretical calculations in the light of previously reported experimental data for these compounds in the solid state. Evidence...
A Raman study of hydroxycinnamic and hydroxybenzoic esters (caffeates, ferulates and gallates) displaying antioxidant and anticancer properties was undertaken, with particular emphasis on the analysis of the effect of the ring substituents and the nature of the ester alkyl chain on their spectroscopic features. A complete assignment of the spectra was carried out for all the compounds investigated, in the light...
A pesquisa arqueológica pré-colonial desenvolvida na região que compreende a bacia hidrográfica do Rio Taquari/Antas identificou a ocupação de grupos horticultores ceramistas, que habitavam e percorriam o território, antecedendo em dez séculos a chegada dos primeiros colonizadores e imigrantes europeus. A presença de evidências cerâmicas, foco desse estudo, pontua e comprova a ocupação deste território. A coleç...
2007
No presente trabalho apresentam-se dados das razões isotópicas 87Sr/86Sr e143Nd/144Nd em dois padrões de rocha do USGS (BCR-1 e STM-1) e três padrões do NIST (SRM 607, 610 e 613) obtidos no Laboratório de Geologia Isotópica da Universidade de Aveiro (LGI-UA) por espectrometria de massa. Os dados obtidos contribuem para a caracterização isotópica destes materiais dada a boa reprodutibilidade e exactidão das aná...
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