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Vulvoperineal Crohn's disease responsive to metronidazole

Rosmaninho, A.; Sanches, M.; Salgado, M.; Alves, R.; Selores, M.

Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and...


Photo-Detectors Integrated with Resonant Tunneling Diodes

Bruno Romeira; Luís M. Pessoa; Henrique M. Salgado; Charles N. Ironside; José M. L. Figueiredo

We report on photo-detectors consisting of an optical waveguide that incorporates a resonant tunneling diode (RTD). Operating at wavelengths around 1.55 μm in the optical communications C band we achieve maximum sensitivities of around 0.29 A/W which is dependent on the bias voltage. This is due to the nature of RTD nonlinear current-voltage characteristic that has a negative differential resistance (NDR) ...


Angiogenic potential of gellan gum-based hydrogels for application in nucleus p...

Correia, Joana Silva; Gonçalves, Vera M.; Salgado, A. J.; Sousa, Nuno; Oliveira, Joaquim M.; Reis, R. M.; Reis, R. L.

Hydrogels for nucleus pulposus (NP) regeneration should be able to comprise a nonangiogenic or even antiangiogenic feature. Gellan gum (GG)–based hydrogels have been reported to possess adequate properties for being used as NP substitutes in acellular and cellular strategies, due to its ability to support cell encapsulation, adequate mechanical properties, and noncytotoxicity. In this study, the angiogenic resp...


Hydrological Modeling in temporary streams: A case study in Pardiela basin, Sou...

PEDRO, A.; MORAIS, M.; ROSADO, J.; SILVA, H.; SERAFIM, A.; NEVES, R.; BRITO, D.; POTES, M.; SALGADO, R.; LILLEBØ, I.; CHAMBEL, A.

The project “Conservation and rehabilitation strategies for temporary Mediterranean river corridors: a case study on Pardiela basin, southern Portugal (Guadiana basin)", is being carried out,with the collaboration of researchers from diverse scientific areas, in order to increase the knowledge on temporary streams. The project includes different approaches at reach and basin scales, regarding the study of tempo...


O Brasil no contexto de controle de qualidade de plantas medicinais

Souza-Moreira,Tatiana M.; Salgado,Hérida R. N.; Pietro,Rosemeire C. L. R.

Atualmente, as plantas medicinais movem altos valores financeiros em todo o mundo e representam o tipo de tratamento mais acessível para cerca de 80% da população, principalmente entre os países em desenvolvimento. Entretanto, existe ainda uma falta de conhecimento sobre propriedades químicas, farmacológicas e toxicológicas a fim de assegurar a eficácia e segurança das plantas medicinais. Os critérios de eficác...

Data: 2010   |   Origem: OASIS br

Ovariectomy does not affect the cardiac sympathovagal balance of female SHR but...

Dias,D.P.M.; Oliveira,M.; Salgado,H.C.; Fazan Jr.,R.

The low incidence of cardiovascular diseases, including hypertension, in premenopausal women has led to the conclusion that ovarian hormones may have a protective effect on the cardiovascular system. We evaluated the effects of ovariectomy and/or estradiol on sympathovagal balance and heart rate variability (HRV) in female spontaneously hypertensive rats (SHR) with tachycardia and compared them to Wistar rats (...

Data: 2010   |   Origem: OASIS br

Monitoring renal function: measured and estimated glomerular filtration rates -...

Salgado,J.V.; Neves,F.A.; Bastos,M.G.; França,A.K.; Brito,D.J.; Santos,E.M.; Salgado Filho,N.

Chronic kidney disease (CKD) is a world-wide public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and premature death. This finding has led to the hypothesis that earlier recognition of kidney disease and successful intervention may improve outcome. The National Kidney Foundation, through its Kidney Disease Outcomes Quality Initiative (K/DOQI), and other National institutions ...

Data: 2010   |   Origem: OASIS br

SAFE-PORT project: an Approach to Port Surveillance and Protection

Martins, M.; Casimiro, R. P.; Gonçalves, S.; Rodrigues, A.; Captivo, M. E.; Gonçalves, G.; Sousa, J.; Calado, J.; Manso, M.; Lopes, J.; Freitas, J. C.

SAFE-PORT is a recently started project addressing the complex issue of determining the best configurations of resources for harbour and port surveillance and protection. More specifically, the main goal is to find, for any given scenario, an adequate set of configuration solutions - i.e., number and type of sensors and equipments, their locations and operating modes, the corresponding personnel and other suppo...


The Safe-Port project: an approach to port surveillance and protection

Martins, M.; Casimiro, R.P.; Gonçalves, S.; Rodrigues, A.; Captivo, M.E.; Gonçalves, G.; Sousa, J.; Calado, J.; Manso, M.; Lopes, J.; Freitas, J.C.

SAFE-PORT is a recently started project addressing the complex issue of determining the best configurations of resources for harbour and port surveillance and protection. More specifically, the main goal is to find, for any given scenario, an adequate set of configuration solutions — i.e., number and type of sensors and equipments, their locations and operating modes, the corresponding personnel and other suppo...


Dendrimers and derivatives as a potential therapeutic tool in regenerative medi...

Oliveira, Joaquim M.; Salgado, A. J.; Sousa, Nuno; Mano, J. F.; Reis, R. L.

Since the pioneering work dealing with the synthesis and physicochemical aspects of dendrimers, a predictable and tunable set of compositions for therapeutic, scaffolding and imaging systems has been reported. These are well documented, butmanyhot issues should be examined and reviewed. Herein, a review is given on dendritic nanopolymers and their applications that show promise in the field of regenerative medi...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia