Despite the wide acceptance that glycans are centrally implicated in immunity, exactly how they contribute to the tilt immune response remains poorly defined. In this study, we sought to evaluate the impact of the malignant phenotype-associated glycan, sialyl-Tn (STn) in the function of the key orchestrators of the immune response, the dendritic cells (DCs). In high grade bladder cancer tissue, the STn antigen ...
Calciphylaxis is a rare and devastating obliterative vasculopathy, leading to ischemia and subcutaneous necrosis. In most cases it affects patients with renal disease and is associated with high morbidity and mortality. We present two case reports followed recently in our department, and a literature review on this topic. Case one refers to an 80 -year -old Caucasian woman with chronic kidney disease stage 5 an...
A malformação quística adenometoideia congénita do pulmão consiste numa massa de quistos revestidos por epitélio respiratório resultante da proliferação dos bronquíolos terminais.A sua apresentação clínica é muito diversa, desde casos de morte fetal por hidrops não imune até quadros de infecções pulmonares recorrentes na infância.Os autores descrevem dois casos clínicos de malformação quística adenomatoideia co...
A prática da pleurodese com substâncias biológicas de características adesivas, tem sido utilizada correntemente em adultos com Fistula Broncopleural (FBP), no entanto, as referências relativas ao seu uso na idade pediátrica são muito escassas.Os autores apresentam um caso de encerramento, com sucesso, de FBP mediante pleurodese com cola de fibrina num recémnascido internado por pneumonia e pneumotórax, submeti...
This study hypothesizes the existence of three groups of sea lamprey Petromyzon marinus L. in Portugal (North/Central group, Tagus group, and Guadiana group), possibly promoted by seabed topography isolation during the oceanic phase of the life cycle. Within this context, our purpose was to analyze the existence of a stock structure on sea lamprey populations sampled in the major Portuguese river basins using b...
In this paper is presented a WDM-ring TDM-tree passive optical network able to provide more than 1024 users spread over 100km with a symmetrical bandwidth of 100Mbps. A set of optically fed passive remote nodes are also presented able to provide increased efficiency and resili90ency. ; In this paper is presented a WDM-ring TDM-tree passive optical network able to provide more than 1024 users spread over 100km ...
This paper addresses an coherent fiber communication analyzer with digital signal processing (DSP). First we make an overview of the investigations that are being conducted at Instituto de Telecomunicações (IT) in the coherent communications area and then introduce the coherent receiver used in the IT laboratory. We also present an interface developed in GUI of Matlab to analyze coherent signals. ...
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