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Understanding APP-dependent neuronal differentiation
Rocha, Joana Fernandes daAmyloid Precursor Protein (APP) is a type 1 membrane protein that suffers proteolytic cleavages and has been implicated in roles such as cell adherence, survival, migration and differentiation. Although a role in neuritogenesis has been attributed to APP, some contradictory results have been reported regarding the benefits of knocking-down or overexpressing APP. Further, while the addition of the APP proteolyti...
Data: 2011
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Origem: RIA - Repositório Institucional da Universidade de Aveiro
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