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An inelastic neutron scattering study of dietary phenolic acids

Marques, M. P. M.; Batista de Carvalho, Luís A. E.; Valero, Rosendo; Machado, Nelson F. L.; Parker, Stewart F.

The conformational preferences and hydrogen-bonding motifs of several potential chemopreventive hydroxycinnamic derivatives were determined by inelastic neutron scattering spectroscopy. The aim is to understand their recognized beneficial activity and establish reliable structure–activity relationships for these types of dietary phytochemicals. A series of phenolic acids with different hydroxyl/methoxyl ring su...



Urticaria after ingestion of alcoholic beverages.

Ribeiro, F; Sousa, N; Carrapatoso, I; Segorbe-Luís, A


Deterioration modeling of steel moment resisting frames using finite-length pla...

Ribeiro, Filipe; Barbosa, Andre R.; Scott, Michael H.; Neves, Luis A. C.

Data: 2014   |   Origem: Repositório Institucional da UNL

Experimental performance comparison of indoor positioning algorithms based on r...

Silva, Hélder D.; Afonso, José A.; Rocha, Luís A.

Publicado em "Proceedings of the World Congress on Engineering 2014, vol. 1. ISBN 978-988-19252-7-5" ; The work presented here compares the performance of indoor positioning systems suitable for low power wireless sensor networks. Map matching, approximate positioning (weighted centroid) and exact positioning algorithms (least squares) were tested and compared in a small predefined indoor environment. We found...


A telerehabilitation system based on wireless motion capture sensors

Macedo, Pedro; Afonso, José A.; Rocha, Luís A.; Simões, Ricardo

The constant growth of the elderly population in the world creates new challenges and opportunities in health care systems. New technological solutions have to be found in order to meet the needs and demands of our aging society. The welfare and quality of life of the elderly population must be a priority. Continuous physical activity will play an important role, due to the increase of the retirement age. Howev...


Diffusion coefficients of 2,2,2-trifluoroethanol/water mixtures

Pereira, Luís A. M.; Ramalho, João P. P.; Carvalho, Alfredo J. P.; Morgado, Pedro; Filipe, Eduardo J. M.; Martins, Luís F. G.

Aqueous mixtures of 2,2,2-trifluoroethanol have received significant attention in the last years because their applications, such as working fluid in Rankine cycle thermal engines or as solvent in studies of protein stability (protein folding). From the fundamental point of view, fluoroalcohols have an amphyphile character, due to the simultaneous presence of a hydrophobic (and alkane-phobic) fluorinated surfac...


A Condenação à Prática de Acto Devido

Vale, Luís A. M. Meneses do

Estudo apresentado no Curso de Mestrado em Ciências Jurídico-Políticas da Faculdade de Direito da Universidade de Coimbra, na disciplina de Direito Administrativo, leccionada pelo Professor Doutor José Carlos Vieira de Andrade


New sustained release of Zidovudine Matrix tablets − cytotoxicity toward Caco-2...

Santos, Jucimary V.; Pina, Maria Eugénia T.; Marques, M. P. M.; Batista de Carvalho, Luís A. E.

Objective: The aim of this study was to adjust the zidovudine (AZT) release from solid tablets to an ideal profile, by developing matrices comprising swellable polymers with nonswellable ones. Methods: Directly compressed matrices comprised different ratios of hydroxypropylmethylcellulose K15M and K100M, ethylcellulose, and methacrylic acid (Eudragit® RS PO and Eudragit® RL PO) were prepared. Technological char...


Applying vibrational spectroscopy to the study of nucleobases – adenine as a ca...

Lopes, Rui P.; Valero, Rosendo; Tomkinson, John; Marques, M. P. M.; Batista de Carvalho, Luís A. E.

A full conformational study of solid-state anhydrous adenine is reported, using vibrational spectroscopy techniques coupled to DFT calculations, for the isolated molecule and the solid. In both cases, the N9Hamino tautomer was found to be the predominant species, followed by the N7H-amino form. An excellent agreement was achieved between experiment and theory, both for wavenumbers and intensities (without the n...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia