Encontrado 1 documento, a visualizar página 1 de 1
Ordenado por
Data
ir para a página:
1
Inactivation of Caspase-1 in Rodent Brain: A Novel Anticonvulsive Strategy
Ravizza, Teresa; Lucas, Sian-Marie; Balosso, Silvia; Bernardino, Liliana; Ku, George; Noé, Francesco; Malva, João; Randle, John C. R.; Allan, StuartPurpose: Cytokines and related inflammatory mediators are rapidly synthesized in the brain during seizures. We previously found that intracerebral administration of interleukin-1 (IL-1)-03B2 has proconvulsant effects, whereas its endogenous receptor antagonist (IL-1Ra) mediates potent anticonvulsant actions in various models of limbic seizures. In this study, we investigated whether seizures can be effectively ...
Data: 2006
|
Origem: Estudo Geral - Universidade de Coimbra
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||