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Síndrome do bebé abanado – experiência de 10 anos de um Serviço de Cuidados Int...

Introdução: O Síndrome do Bebé Abanado é uma das causas de lesão não acidental mais difíceis de diagnosticar. Objetivos: Caracterizar os doentes internados no Serviço de Cuidados Intensivos Pediátricos (SCIP) com Síndrome do Bebé Abanado. Material e Métodos: Estudo retrospetivo dos doentes internados no SCIP do Centro Hospitalar de São João com o diagnóstico de Síndrome de Bebé Abanado de 1 de Janeiro de 1999 a...

Rastreio de cancro colo-retal e vigilância de lesões precursoras: protocolo hos...

Envolvimento hepático na telangiectasia hemorrágica hereditária

O envolvimento hepático na Telangiectasia Hemorrágica Hereditária (THH) é raro e, na maioria dos casos, é assintomático e não carece de terapêutica específica. No entanto, apresenta alterações hepáticas que fazem diagnóstico diferencial com entidades mais frequentes e clinicamente mais significativas, como a doença hepática crónica, a cirrose ou mesmo o carcinoma hepatocelular. O diagnóstico errado trará angús...

Liver involvement in hereditary haemorrhagic telangiectasia (HHT; Osler-Weber-R...

Extraction with supercritical fluid and comparison of chemical composition from...

Plants differ in metabolism during their life cycle. In species used as phytotherapics, these changes determine the quality and effectiveness of the product. The aim of this study to evaluate the differences of chemical extracts obtained with supercritical CO2 from young and adult leaves of Zanthoxylum tingoassuiba St.-Hil., Rutaceae, a species used in the folk medicine in Brazil. The chemical composition of th...

Quality, innovation and performance: an exploratory study

The relationship between total quality management and innovation appears contradictory and complex. Literature suggests that conflicting arguments exist and while for some researchers, total quality management practices do not directly improve innovation, for others, there is a positive relationship between management practices of quality and innovation. Similarly, it remains to explain the influence of total q...

Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated w...

Abstract BACKGROUND: CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly mor...

Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated w...

CD4+CD25+ regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly more frequent in females...

Low frequency of CD4(+) CD25(+) Treg in SLE patients: a heritable trait associa...

Background: CD4(+)CD25(+) regulatory T cells play an essential role in maintaining immune homeostasis and preventing autoimmunity. Therefore, defects in Treg development, maintenance or function have been associated with several human autoimmune diseases including Systemic Lupus Erythematosus (SLE), a systemic autoimmune disease characterized by loss of tolerance to nuclear components and significantly more fre...

Spectrophotometric study of the chromium(III)/azide system in the ultraviolet r...

A sensitive and alternative method for the spectrophotometric determination of chromium(III) based on the formation of chromium(III)/azide complexes was established by investigating a new band in the ultraviolet region. The best experimental conditions for the analytical determination of this metallic ion were: ligand and perchloric acid analytical concentration = 493 and 12.0 mmol L-1, respectively; aqueous me...