Encontrados 11 documentos, a visualizar página 1 de 2
Recommendations for Mutational Analysis in Gastrointestinal Stromal Tumors (GIS...
Lopes, J M; Faculdade de Medicina do Porto, Serviço de Anatomia Patológica do Centro Hospitalar de S.João, e IPATIMUP, Porto - PortugalGIST Portuguese Working Group – Condeixa ProposalThe authors outline recommendations for the mutational analysis of GISTs unanimously approved by a multidisciplinary group on July 20th, 2062. The mutational status of KIT and PDGFRA allows identifying therapeutic targets to tyrosine kinase inhibitors (TKIs), and therefore, the safe clinical practice in the biotherapy decisions for patients with GISTs should incl...
Nociceptive behaviour upon modulation of mu-opioid receptors in the ventrobasal...
Daniel Pozza; Catarina Potes; Patricia Barroso; Luís Azevedo; Castro Lopes J.M.; Fani NetoThe role of mu-opioid receptors (MORs) in the inflammatory pain processing mechanisms within the ventrobasal complex of the thalamus (VB) is not well understood. This study investigated the effect of modulating MOR activity upon nociception, by stereotaxically injecting specific ligands in the VB. Nociceptive behaviour was evaluated in two established animal models of inflammatory pain, by using the formalin (a...
Acute generalized exanthematous pustulosis associated with diltiazem.
Serrão, Vasco; Caldas Lopes, Luísa; Campos Lopes, J M; Lobo, Lurdes; Ferreira, AnaAcute generalized exanthematous pustulosis (AGEP) usually presents with the acute appearance of oedematous and erythematous lesions, on which multiple sterile pustules appear, associated with fever. Almost 90% of cases are associated with drugs, with antibiotics (penicillins and macrolides) being the most frequent causative agents. We describe a 36-year-old female patient, which started diltiazem 120mg/day for ...
Comparative study of Al-MCM materials prepared at room temperature with differe...
Ribeiro Carrott, Manuela; Conceição, Filipe; Lopes, J.M.; Carrott, Peter; Bernardes, C.; Rocha, J.; Ribeiro, F. RamôaA comparison of the pore structural properties and catalytic activity of MCM-41 containing aluminium, prepared at room temperature with different aluminium sources, is presented. In addition, they are compared with those of MCM-41 obtained by two conventional hydrothermal procedures and room temperature synthesised Al-MCM-48 grades. Al-MCM-41 samples were prepared by direct synthesis at room temperature with te...
Genetic alterations of adult and paediatric astrocytic tumours
Reis, R. M.; Lopes, J. M.Astocytic tumours represent the most frequent adult and paediatric brain tumours. Central nervous system (CNS) tumours are the second most frequent paediatric malignancies. Astrocytic tumours are a heterogeneous group, composed of different histological and biological subtypes organized into four grades of malignancy. Malignant astocytic tumours occur preferentially in adults, diffusely infiltrate the surroundi...
Protocolos otimizados para arranjamentos de clones e minipreparação de DNA
LABUTO, L. B. D.; LOPES, J. M. P.; SOUSA, Z. A. dos R.; ANDRADE, V. do N.; BORGES NETO, C. R.2003
Intraclonal diversity in a Sezary syndrome with a differential response to 2‐de...
GRANJO, E.; LIMA, M.; LOPES, J.M.; CUNHA, N.; TEIXEIRA, M. A.; SANTOS, F.; CANDEIAS, J.; RESENDE, C.; SANTOS, A.H.; BALANZATEGUI, A.; ORFAO, A.Br J Haematol. 2002 Dec;119(3):629-33. Intraclonal diversity in a Sezary syndrome with a differential response to 2-deoxycoformycin of the two lymphoma cell populations. Granjo E, Lima M, Lopes JM, Cunha N, Teixeira Mdos A, Santos F, Candeias J, Resende C, Santos AH, Balanzategui A, Orfão A, Matutes E. Department of Clinical Haematology, Hospital Geral de São João, Porto, Portugal. npp46740@mail.telpac.pt Ab...
Chronic eosinophilic leukaemia presenting with erythroderma, mild eosinophilia ...
GRANJO, E.; LIMA, M.; LOPES, J.M.; DORIA, S.; ORFAO, A.; YING, S.; BARATA, L.T.; MIRANDA, M.; CROSS, N.C.; BAIN, B.J.Acta Haematol. 2002;107(2):108-12. Chronic eosinophilic leukaemia presenting with erythroderma, mild eosinophilia and hyper-IgE: clinical, immunological and cytogenetic features and therapeutic approach. A case report. Granjo E, Lima M, Lopes JM, Dória S, Orfão A, Ying S, Barata LT, Miranda M, Cross NC, Bain BJ. Department of Clinical Haematology, Hospital Geral de São João, Porto, Portugal. elisagranjo@netc....
Sheehan's syndrome.
Godinho, N; Serviço de Medicina, Hospital de Santa Marta, Lisboa.; Lopes, J M; Augusto, V V; Eliseu, T; da Silva, P M; Bastos, H; Nobre, F LThe authors describe a case of Sheehan's syndrome that followed hemorrhagic complications due to late abortion, and emphasise the infrequency of changes in plasma lipid levels in this disease. They report a particular case of hypopituitarism and point out the main concepts of pathophysiology, diagnosis, therapeutics and complications that follow this increasingly rarer condition. ; The authors describe a case ...
Interaction of the contents of alcoholic beverages in the promotion of liver da...
Peneda, J; Hospital dos Capuchos, Centro de Anatomia Patológica, Hospital Universitário de Santa Maria, Lisboa.; Baptista, A; Lopes, J MThe adverse effects of the exposure of the liver to the interaction of ethanol with its congeners and acetaldehyde, coexisting in the contents of alcoholic beverages, have been little studied. Twenty four male Wistar rats were divided into four groups. Two groups (SH/DA; SH/FA) were submitted to daily treatment with synthetic hydroalcoholic solutions containing ethanol, methanol, higher alcohols and acetaldehyd...
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