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PHEOCHROMOCYTOMA AND NEUROFIBROMATOSIS 1

Introduction: Pheochromocytomas are tumours arising from chromaffin cells in the sympathetic nervous system. Clinical manifestations are protean, function of the variable secretory profile of several compounds including catecolamines, neuropeptides and other vasoactive molecules. Neurofibromatosis I (von Recklinghausen`s disease), a prevalent autosomal dominant disorder, is the most prevalent type among the neu...

A lactate shuttle system between tumour and stromal cells is associated with po...

Background In a malignant tumour, cancer cells are embedded in stromal cells, namely cancer-associated fibroblasts (CAFs). These CAFs are now accepted as important players in cancer dynamics, being involved in tumour growth and progression. Although there are various reports on the interaction between tumour and stromal cells, the clinico-pathological significance of this cross-talk is still largely unknown. In...

Bibliotecas do Ensino Superior: Exigências do Futuro

Bibliotecas do Ensino Superior: Exigências do Futuro

The impact of the Online Knowledge Library: its use and impact on the productio...

In recent years several initiatives have taken place to promote universal access to the Information and Knowledge Society. It was in this context that in 2004 the Online Knowledge Library (b-on) was launched in Portugal. With it, it became easier to get access to full text international scientific publications. This study aims to present and analyse some of the statistical and bibliometric indicators of the Por...

Sistema de indicadores de desenvolvimento sustentável local : estudo de caso no...

Trabalho de projecto em Cidadania Ambiental e Participação apresentadado à Universidade Aberta ; Os municípios possuem competências para atuar na promoção de políticas e ações que favoreçam o desenvolvimento local de forma sustentada e equilibrada. O desenvolvimento local não se centra unicamente no desenvolvimento económico, mas também na qualidade de vida dos munícipes, na preservação do ambiente, na diversi...

Carcinogenic Ability of Schistosoma Haematobium Possibly through Oncogenic Muta...

Schistosoma haematobium is a parasitic flatworm that infects millions of people, mostly in the developing world, and is associated with high incidence of bladder cancer, although why is not clear. Previously, we have used CD-1 mice to show that Schistosoma haematobium total antigen (Sh) has a carcinogenic ability. Sh intravesically instillation induced the development of several urothelial lesions, namely nodul...

The impact of the online knowledge library: Its use and impact on the productio...

In recent years several initiatives have taken place to promote universal access to the Information and Knowledge Society. It was in this context that in 2004 the Online Knowledge Library (b-on) was launched in Portugal. With it, it became easier to get access to full text international scientific publications. This study aims to present and analyse some of the statistical and bibliometric indicators of the Por...

B-on’s evolution and its contribution to the development of Portuguese science

In recent years several initiatives have taken place to promote universal access to the Information and Knowledge Society. It was in this context that in 2004 the Online Knowledge Library (bon) was launched in Portugal. With it, it became easier to get access to full text international scientific publications. This study aims to present and analyze some bibliometric indicators of the Portuguese scientific outpu...

Comparative leaf micromorphoanatomy of Vitis vinifera SSP.vinifera (Vitaceae) r...

Aiming to characterize and discriminate between four red grapevine cultivars – ‘Aragonez’ (AR), ‘Cabernet Sauvignon’ (CS), ‘Syrah’ (SY) and ‘Touriga Nacional’ (TN) – grown under Mediterranean field conditions, we studied their leaf micromorphoanatomic characteristics under light (LM) and scanning electron microscopy (SEM). The studied characteristics included those of the epidermis, stomata and hair distributio...

Effects of the atmospheric vapour pressure deficit and soil water availability ...