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Human mesenchymal stem cells response to multi-doped silicon-strontium calcium ...
Rodríguez-Valencia, Cosme; Pereiro, Iago; Pirraco, Rogério; Lopéz-Álvarez, M.; Serra, J.; González, P.; Marques, A. P.; Reis, R. L.The search for apatitic calcium phosphate coatings to improve implants osteointegration is, nowadays, preferentially focused in the obtaining of compositions closer to that of the inorganic phase of bone. Silicon and strontium are both present in trace concentrations in natural bone and have been demonstrated, by separate, to significantly improve osteoblastic response on calcium phosphate bioceramics. This wor...
Silicon-hydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and s...
Lopez-Alvarez, M.; Solla, E. L.; Gonzalez, P.; Serra, J.; Leon, Bétty; Marques, A. P.; Reis, R. L.The aim of this study consisted on investigating the influence of silicon substituted hydroxyapatite (Si–HA) coatings over the human osteoblast-like cell line (SaOS-2) behaviour. Diatomaceous earth and silica, together with commercial hydroxyapatite were respectively the silicon and HA sources used to produce the Si–HA coatings. HA coatings with 0 wt% of silicon were used as control of the experiment. Pulsed la...
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