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The impact of GGH -401C>T polymorphism on cisplatin-based chemoradiotherapy res...
Silva, Inês Hilário; Silva, Cristina Nogueira; Figueiredo, Tiago; Lombo, Liliana; Faustino, Ilda; Catarino, Raquel; Nogueira, Augusto; Pereira, DeolindaUncorrected proof ; Aims: Cervical cancer is the third most frequent cancer in women worldwide, mostly treated with cisplatin-based chemoradiotherapy. Since it is known that folate metabolism might interfere with cisplatin effectiveness, we intended to study the influence of the Gamma Glutamyl Hydrolase -401C > T polymorphism in treatment response in cervical cancer. Methods: We retrospectively reviewed the ...
Data: 2012
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Origem: RepositóriUM - Universidade do Minho
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