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Noninvasive evaluation of retinal leakage using optical coherence tomography

Bernardes, Rui; Santos, Torcato; Serranho, Pedro; Lobo, Conceição; Cunha-Vaz, José

Purpose: To demonstrate the association between changes in the blood-retinal barrier (BRB) identified by fluorescein leakage and those in the optical properties of the human retina determined by optical coherence tomography (OCT) and show how these changes can be quantified and their location identified within the retina. Methods: Two imaging techniques were applied: the retinal leakage analyzer, to map BRB fun...


Digital ocular fundus imaging: a review

Bernardes, Rui; Serranho, Pedro; Lobo, Conceição

Ocular fundus imaging plays a key role in monitoring the health status of the human eye. Currently, a large number of imaging modalities allow the assessment and/or quantification of ocular changes from a healthy status. This review focuses on the main digital fundus imaging modality, color fundus photography, with a brief overview of complementary techniques, such as fluorescein angiography. While focusing on ...


Macular alterations after small-incision cataract surgery

Lobo, Conceição L.; Faria, Pedro M.; Soares, Mário A.; Bernardes, Rui C.; Cunha-Vaz, José G.

Purpose: To characterize macular edema that occurs after uneventful cataract surgery. ; http://www.sciencedirect.com/science/article/B6VSF-4C54BTG-N/1/fba2fd923592d5172c5e0a4f69426a61


Alterations of retinal capillary blood flow in preclinical retinopathy in subje...

Ludovico, José; Bernardes, Rui; Pires, Isabel; Figueira, João; Lobo, Conceição; Cunha-Vaz, José

Background: To identify alterations of retinal capillary blood flow in the papillomacular area in preclinical diabetic retinopathy using the Heidelberg scanning laser Doppler flowmeter. Methods: Ten eyes from ten patients with type 2 diabetes and no lesions visible on fundus photography (level 10 of Wisconsin grading) and ten eyes from ten healthy subjects of similar age range were examined with the HRF. Intrav...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia