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Liposomes as a model for the biological membrane : studies on daunorubicin bila...
Matos, C.; Moutinho, C.; Lobão, P.In this study the interaction of the antitumoral drug daunorubicin with egg phosphatidylcholine (EPC) liposomes, used as a cell membrane model, was quantified by determination of the partition coefficient (Kp). The liposome/aqueous-phase Kp of daunorubicin was determined by derivative spectrophotometry and measurement of the zeta-potential. Mathematical models were used to fit the experimental data, enabling de...
Data: 2012
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Origem: RepositóriUM - Universidade do Minho
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