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Thyroid hormone receptor expression during metamorphosis of Atlantic halibut (H...
Galay-Burgos, Malyka; Power, Deborah; Llewellyn, Lynda; Sweeney, Glen E.Flatfish such as the Atlantic halibut (Hippoglossus hippoglossus) undergo a dramatic metamorphosis that transforms the pelagic, symmetric larva into a benthic, cranially asymmetric juvenile. In common with amphibian metamorphosis, flatfish metamorphosis is under endocrine control with thyroid hormones being particularly important. In this report we confirm that tri-iodothyronine (T3) levels peak at metamorphic ...
Troponin T isoform expression is modulated during Atlantic Halibut metamorphosis
Campinho, M. A.; Silva, Nadia; Nowell, Mari A.; Llewellyn, Lynda; Sweeney, Glen E.; Power, DeborahBackground: Flatfish metamorphosis is a thyroid hormone (TH) driven process which leads to a dramatic change from a symmetrical larva to an asymmetrical juvenile. The effect of THs on muscle and in particular muscle sarcomer protein genes is largely unexplored in fish. The change in Troponin T (TnT), a pivotal protein in the assembly of skeletal muscles sarcomeres and a modulator of calcium driven muscle contra...
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