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In vivo MRI assessment of a novel GdIII-based contrast agent designed for high ...
Sousa, Paulo Loureiro de; Livramento, João Bruno; Helm, Lothar; Merbach, André E.; Même, William; Doan, Bich-Thuy; Beloeil, Jean-ClaudeGd3L is a trinuclear Gd3+ complex of intermediate size, designed for contrast agent applications in high field magnetic resonance imaging (H12L is based on a trimethylbenzene core bearing three methylene-diethylenetriamine- N,N,NPrimeNPrime-tetraacetate moieties). Thanks to its appropriate size, the presence of two inner sphere water molecules and a fast water exchange, Gd3L has remarkable proton relaxivities a...
Data: 2008
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Origem: Estudo Geral - Universidade de Coimbra
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