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GAGs-thiolated chitosan assemblies for chronic wounds treatment : control of en...

Multilayered polyelectrolyte coatings comprising thiolated chitosan (TC) and glycosaminoglycans (GAGs), chondroitin sulphate and hyaluronic acid, were built using a layer-by-layer approach. The surface activity of these coatings for binding and inhibition of enzymes related to chronic inflammation, such as collagenase and myeloperoxidase, was assessed. The build-up of five bi-layers of TC/GAGs onto gold surface...

Thiolated chitosan/glycosaminoglycans multilayered films : QCM-D study on the f...

Layer-by-layer technique is widely used to produce polyelectrolyte multilayered films for material surface functionalization. The technique simplicity coupled with the biological potential of biopolymers, e.g. polysaccharides, make such assemblies a suitable choice for many biomedical applications. In this study the formation of the films comprising of thiolated chitosan and glycosaminoglycans (GAGs) by alterna...

Innovative 2D/3D biotextiles for potential bone tissue engineering applications

Bone tissue engineering represents a specialised niche within the biomedical field to which textile technologies can markedly contribute. Textile-based technologies are considered as potential routes for the production of scaffolds for TE applications, as they present superior control over design and reproducibility. This work aims at developing novel 2D/3D textile structures based on different polymeric materi...

Effect of medroxyprogesterone acetate on thyrotropin secretion in adult and old...

Steroid hormones have been implicated in the modulation of TSH secretion; however, there are few and controversial data regarding the effect of progesterone (Pg) on TSH secretion. Medroxyprogesterone acetate (MPA) is a synthetic alpha-hydroxyprogesterone analog that has been extensively employed in therapeutics for its Pg-like actions, but that also has some glucocorticoid and androgen activity. Both hormones h...

Dose-dependent effects of 17-ß-estradiol on pituitary thyrotropin content and s...

We studied the basal and thyrotropin-releasing hormone (TRH) (50 nM) induced thyrotropin (TSH) release in isolated hemipituitaries of ovariectomized rats treated with near-physiological or high doses of 17-ß-estradiol benzoate (EB; sc, daily for 10 days) or with vehicle (untreated control rats, OVX). One group was sham-operated (normal control). The anterior pituitary glands were incubated in Krebs-Ringer bicar...

Effects of estradiol benzoate on 5'-iodothyronine deiodinase activities in fema...

There is little information on the possible effects of estrogen on the activity of 5'-deiodinase (5'-ID), an enzyme responsible for the generation of T3, the biologically active thyroid hormone. In the present study, anterior pituitary sonicates or hepatic and thyroid microsomes from ovariectomized (OVX) rats treated or not with estradiol benzoate (EB, 0.7 or 14 µg/100 g body weight, sc, for 10 days) were assay...

Insetos pragas de madeiras de edificações em Belém - Pará.

1989

Microalbuminuria in type I and type II diabetics without hypertension. A preview.

Longitudinal study of the concentration of serum fructosamine in diabetic patie...

N-acetyl-beta-D-glucosaminidase activity in relation to blood glucose, serum fr...