Cell-based therapies for regenerative medicine have been characterized by the low retention and integration of injected cells into host structures. Cell immobilization in hydrogels for target cell delivery has been developed to circumvent this issue. In this work mesenchymal stem cells isolated from Wistar rats bone marrow (rMSCs) were immobilized in alginate beads fabricated using an innovative approach involv...
Encapsulating technologies that render spherical particles containing cells or relevant moleculeshave been developed to be used in fields such as tissue engineering, pharmaceutics, cosmetics, agriculture, as also in other bio-related applications, namely biosensors and bioreactors. The multiple bioactive agents release, with an important role in tissue regeneration, constitutes an important strategy in tissue e...
The low retention/integration of injected cells by host structures represents an important challenge in cell based therapies for regenerative medicine purposes. Cell immobilization in hydrogels for target cell delivery has been developed to circumvent this issue. However, the existing immobilization methodologies sometimes have several steps under wet conditions and present some drawbacks, including poor encaps...
Purpose: To implement a bioinspired methodology using superhydrophobic surfaces suitable for producing smart hydro- gel beads in which the bioactive substance is introduced in the particles during their formation. Methods: Several superhydrophobic surfaces, including polystyrene, aluminum and copper, were prepared. Polymeric solutions composed by photo-crosslinked dextran-methacrylated and thermal responsive p...
2010 ; A biblioteca possui um exemplar na seção Produção Científica da unidade
The aim of this study was to test the hypothesis of differences in performance including differences in ST-T wave changes between healthy men and women submitted to an exercise stress test. Two hundred (45.4%) men and 241 (54.6%) women (mean age: 38.7 ± 11.0 years) were submitted to an exercise stress test. Physiologic and electrocardiographic variables were compared by the Student t-test and the chi-square tes...
It has been demonstrated that there is an association between serum lipoproteins and survival rate in patients with ischemic cardiomyopathy, as well as in patients with non-ischemic causes of heart failure. We tested the hypothesis of an association between serum lipoprotein levels and prognosis in a cohort of outpatients with heart failure, including Chagas' heart disease. The lipid profile of 833 outpatients ...
2007
Definição do produto; Etapas do processo de produção; Equipamentos e utensílios; Planta baixa da agroindústria; Higienização do ambiente, de equipamentos e de utensílios; Boas práticas de fabricação (BPF). ; 2007
2007
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