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Phenotypic and functional consequences of haploinsufficiency of genes from exoc...
Wen, J.; Lopes, F.; Soares, G.; Farrell, S.; Nelson, C.; Qiao, Y.; Martell, S.; Badukke, C.; Bessa, C.; Ylstra, B.; Lewis, S.; Isoherranen, N.Background Rare, recurrent genomic imbalances facilitate the association of genotype with abnormalities at the “whole body” level. However, at the cellular level, the functional consequences of recurrent genomic abnormalities and how they can be linked to the phenotype are much less investigated. Method and results We report an example of a functional analysis of two genes from a new, overlapping microdeletion...
Mars environment and magnetic orbiter model payload
Langlais, B.; Leblanc, F.; Fouchet, T.; Barabash, S.; Breuer, D.; Chassefière, E.; Coates, A.; Dehant, V.; Forget, F.; Lammer, H.; Lewis, S.Abstract Mars Environment and Magnetic Orbiter was proposed as an answer to the Cosmic Vision Call of Opportunity as a M-class mission. The MEMO mission is designed to study the strong interconnections between the planetary interior, atmosphere and solar conditions essential to understand planetary evolution, the appearance of life and its sustainability. MEMO provides a high-resolution, complete, mapping of t...
Effect of timing and method of enteral tube feeding for dysphagic stroke patien...
Dennis, M.; Lewis, S.; Warlow, C.; FOOD Trial CollaborationSummary Background Undernutrition is common in patients admitted with stroke. We aimed to establish whether the timing and route of enteral tube feeding after stroke affected patients’ outcomes at 6 months. Methods The FOOD trials consist of three pragmatic multicentre randomised controlled trials, two of which included dysphagic stroke patients. In one trial, patients enrolled within 7 days of admission were r...
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