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Improvement of electrospun polymer fiber meshes pore size by femtosecond laser ...
Rebollar, Esther; Cordero, Diego; Martins, Albino; Chiussi, Stefano; Reis, R. L.; Neves, N. M.; Leon, BéttyPolymer meshes have recently attracted great attention due to their great variety of aplications in fields such as tissue engineering and drug delivery. Poly( -caprolactone) nanofibers were prepared by electrospinning giving rise to porous meshes. However, for some applications in tissue engineering where, for instance, cell migration into the inner regions of the mesh is aimed, the pore size obtained by conven...
Surface modification of a biodegradable composite by UV laser ablation : in vit...
Martins, Albino; Gang, Wu; Pinho, Elisabete D.; Rebollar, Esther; Chiussi, Stefano; Reis, R. L.; Leon, Betty; Neves, N. M.Melt blends of chitosan and biodegradable aliphatic polyester have been physically and biologically studied, presenting great potential for biomedical applications. Structurally, poly(butylene succinate)–chitosan (PBS/Cht) composite scaffolds are covered by a thin PBS layer, preventing the desired interaction of cells/tissues with the chitosan particules. In the present work, a selective and controlled ablation...
Silicon-hydroxyapatite bioactive coatings (Si-HA) from diatomaceous earth and s...
Lopez-Alvarez, M.; Solla, E. L.; Gonzalez, P.; Serra, J.; Leon, Bétty; Marques, A. P.; Reis, R. L.The aim of this study consisted on investigating the influence of silicon substituted hydroxyapatite (Si–HA) coatings over the human osteoblast-like cell line (SaOS-2) behaviour. Diatomaceous earth and silica, together with commercial hydroxyapatite were respectively the silicon and HA sources used to produce the Si–HA coatings. HA coatings with 0 wt% of silicon were used as control of the experiment. Pulsed la...
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