The most common causes of anemia are micronutrient deficiencies, but other factors may influence namely inflammation, parasitic infections and inherited disorders. One strategy to combat micronutrient deficiencies is supplementation, yet, in zones with high prevalence of Schistosomiasis or Soil Transmitted Helminthes (STH), supplementation could be not sufficient. The aim of this study was to evaluate the effec...
Introdução - A schistosomíase é um agente causador de anemia e outras manifestações clínicas em crianças, comprometendo o seu crescimento e a sua performance escolar. Actualmente a principal iniciativa de controlo integrado da schistosomíase é a implementação de programas de administração massiva de praziquantel e albendazol na escola ou na comunidade para o controlo da endemia. Objectivo - O objectivo deste es...
Tese de mestrado integrado. Engenharia Civil (especialização em Hidráulica). Faculdade de Engenharia. Universidade do Porto. 2008
The vitamin D receptor (VDR) gene is a candidate gene for susceptibility to autoimmune disorders. Association studies of VDR polymorphisms and risk of type 1 diabetes often produced conflicting results in different ethnic backgrounds. The aim of this study was to test for association between common VDR polymorphisms and the genetic susceptibility to type 1 diabetes in the Portuguese population. We genotyped 207...
Several polymorphisms of drug-metabolizing enzymes have been implicated in the susceptibility to tumor development. The role of the CYP2D6, GSTM1 and GSTT1 genes has been extensively studied, with alleles conferring different metabolic efficiencies and tumor risk. We studied the relationship between the main polymorphisms of these genes and the susceptibility to develop pituitary tumors, by performing a case-co...
Anaplastic thyroid tumor is a rare tumor and constitutes 5 to 10% of thyroid carcinomas. Is one of the most aggressive solid tumors and the prognosis is always fatal with a mean survival of 3 to 7 months. The current therapeutics are scarce and inefficacious. A retrospective analysis was performed in 12 clinical cases of anaplastic thyroid tumor observed at the Department of Endocrinology, Diabetes and Metaboli...
Our aims were to determine the frequency of diabetic hyperosmolality (DH) in our Department, its causes, therapeutic implications and evolution. A five-years retrospective study was performed in 60 patients regarding age, sex, type and duration of diabetes mellitus (DM), previous antidiabetic therapy, underlying diseases, biochemical data, precipitating factors, therapeutic management and outcome.The hyperosmol...
O propósito deste artigo é o de documentar o desenvolvimento de uma plataforma de software que facilite, a utilizadores pouco versados na utilização de ferramentas de edição multimédia, um serviço de composição e publicação de documentos num servidor WWW, disponibilizá-los numa interface Web sob classificação temática , e apoiar nas buscas relativas aos documentos e outros recursos informativos residentes numa ...
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