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Development and Characterization of a Novel Hybrid Tissue Engineering–Based Sca...

Silva, Nuno; Salgado, A. J.; Sousa, R. A.; Oliveira, João T.; Adriano, Pedro; Leite-Almeida, Hugo; Cerqueira, R.; Almeida, Armando; Mastronardi, F.

Spinal cord injury (SCI) represents a significant health and social problem, and therefore it is vital to develop novel strategies that can specifically target it. In this context, the objective of the present work was to develop a new range of three-dimensional (3D) tubular structures aimed at inducing the regeneration within SCI sites. Up to six different 3D tubular structures were initially developed by rapi...


Differential effects of left/right neuropathy on rats’ anxiety and cognitive be...

Leite-Almeida, Hugo; Cerqueira, João; Wei, Hong; Ribeiro, Nuno Costa; Martins, Helena Anjos; Sousa, Nuno; Pertovaara, Antti; Almeida, Armando

Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the body. It has been suggested that such side bias results from cortical function lateralization. It is not known, however, if other pain-associated behavioral chan...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia