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Brain activation of the defensive and appetitive survival systems in obsessive ...

Several studies have shown that basic emotions are responsible for a significant enhancement of early visual processes and increased activation in visual processing brain regions. It may be possible that the cognitive uncertainty and repeated behavioral checking evident in Obsessive Compulsive Disorder (OCD) is due to the existence of abnormalities in basic survival circuits, particularly those associated with ...

Síndrome Febril e Coma. Considerações a Propósito de Um Caso Clínico

A endocardite infecciosa é relativamente pouco frequente na idade pediátrica, mas a sua morbilidade e mortalidade são elevadas.Os autores descrevem um caso clínico de endocardite infecciosa aguda por Staphylococcus aureus numa criança de 5 anos de idade, sem factores de risco conhecidos, diagnosticada na sequência de complicações neurológicas (degradação súbita do estado de consciência e sinais neurológicos foc...

External school evaluation in Portugal: a glance at the impacts on curricular a...

Obsessive Compulsive Disorder as a functional interhemispheric imbalance at the...

Obsessive Compulsive Disorder (OCD) involves failures in two main inhibitory processes, namely cognitive (obsessions) and behavioral (compulsions). Recent research has supported two cortical-subcortical pathways on OCD pathogenesis: (a) the frontostriatal loop (dorsolateral-caudate-striatum-thalamus) responsible for impairments of behavioral inhibition; (b) the orbitofrontal loop (orbitofrontal, medial prefront...

A clinical gamma camera-based pinhole collimated system for high resolution sma...

The main objective of the present study was to upgrade a clinical gamma camera to obtain high resolution tomographic images of small animal organs. The system is based on a clinical gamma camera to which we have adapted a special-purpose pinhole collimator and a device for positioning and rotating the target based on a computer-controlled step motor. We developed a software tool to reconstruct the target’...

Differential patterns of myosin Va expression during the ontogenesis of the rat...

Myosin Va is an actin-based, processive molecular motor protein highly enriched in the nervous tissue of vertebrates. It has been associated with processes of cellular motility, which include organelle transport and neurite outgrowth. The in vivo expression of myosin Va protein in the developing nervous system of mammals has not yet been reported. We describe here the immunolocalization of myosin Va in the deve...

Technique for optimization of ceramic bodies using mixture design

In the production of wall and floor ceramic tiles, mixtures of raw materials from several origins with different physical and chemical characteristics are used. Those changes of raw materials alter the quality of the finished product, what implicates in the constant reformulation in the composition of the ceramic mass through try and error, consuming time and materials. This configures the ideal circumstance to...

Carcinoma pancreático de células gigantes de tipo osteoclástico

Initially described 40 years ago (Rosai), the undifferentiated osteoclastic-type giant cell carcinoma (IOGCC) is a variant of ductal adenocarcinoma and accounts for less than 1% of exocrine pancreatic tumors. Its extreme rarity, with consequent existence of few reports and clinical experience, leads to the arousal of doubts with regard to its histogenesis, types of approach and therapeutical attitudes. It is im...

Detection of caliciviruses associated with acute infantile gastroenteritis in S...

Acute gastroenteritis caused by viruses is one of the leading causes of infantile morbidity. The aim of the present study was to investigate the presence of human caliciviruses of the genera norovirus and sapovirus in children up to 3 years of age with acute gastroenteritis from low-income communities in the city of Salvador, Brazil. This study is an extension of previous work carried out to establish the profi...

Methodological approaches to planar and volumetric scintigraphic imaging of sma...

Single-photon emission computed tomography (SPECT) is a non-invasive imaging technique, which provides information reporting the functional states of tissues. SPECT imaging has been used as a diagnostic tool in several human disorders and can be used in animal models of diseases for physiopathological, genomic and drug discovery studies. However, most of the experimental models used in research involve rodents,...