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Relationship between Protein kinase C and derepression of different enzymes

The PKC1 gene in the yeast Saccharomyces cerevisiae encodes for protein kinase C which is known to control a MAP kinase cascade consisting of different kinases: Bck1, Mkk1 and Mkk2, and Mpk1. This cascade affects the cell wall integrity but the phenotype of pkc1∆ mutants suggests additional targets that have not yet been identified [1]. The pkc1∆ mutant, as opposed to other mutants in the MAP kinase cascade, di...