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Flow visualization of trace particles and red blood cells in a microchannel wit...
Leble, Vladimir; Fernandes, Carla S.; Dias, Ricardo P.; Lima, R.; Ishikawa, Takuji; Imai, Yohsuke; Yamaguchi, TakamiThis paper aims to investigate the effect of both diverging and converging bifurcations on the flow behaviour of pure water (PW) and red blood cells (RBCs). A confocal micro-PTV system is used to visualize and measure the flow characteristics of the working fluids. The results show no formation of a cell-free layer (CFL) around the apex of the bifurcation. In contrast, there is a clear formation of a triangular...
Asymmetry of red blood cell motions in a microchannel with a diverging and conv...
Leble, Vladimir; Lima, R.; Dias, Ricardo P.; Fernandes, Carla S.; Ishikawa, Takuji; Imai, Yohsuke; Yamaguchi, TakamiIn microcirculation, red blood cells (RBCs) flowing through bifurcations may deform considerably due to combination of different phenomena that happen at the micro-scale level, such as: attraction effect, high shear and extensional stress, all of which may influence the rheological properties and flow behavior of blood. Thus, it is important to investigate in detail the behavior of blood flow occurring at both ...
Motions of trace particles and red blood cells in a PDMS microchannel with a co...
Leble, Vladimir; Dias, Ricardo P.; Lima, R.; Fernandes, Carla S.; Ishikawa, Takuji; Imai, Yohsuke; Yamaguchi, TakamiThis paper presents microflow visualizations of both pure water and red blood cells (RBCs) in a converging bifurcation. The visualizations are a combination of results obtained from a confocal micro-PTV system and an image analysis technique known as “Zproject” from ImageJ. Our preliminary qualitative results suggest that the cell-free layer that is formed in middle of the microchannel (after confluence apex) m...
Flow of red blood cells through microchannel with a confluence
Leble, Vladimir; Lima, R.; Fernandes, Carla S.; Dias, Ricardo P.Micro-visualization techniques have been used to investigate the in vitro blood flow through straight glass capillaries. Although the glass microchannels present certain similarities to in vivo microcirculation, it is also clear that these kind of in vitro experiments differ from microvessels in several respects, such as: elasticity of microvessels, effect of the endothelial surface layer and microvascular netw...
Flow of red blood cells in capillary networks
Ribeiro, A. E.; Couto, Ana; Teixeira, Lúcia; Leble, Vladimir; Lima, R.; Dias, RicardoIn the present work we have studied the flow of red blood cells through a column packed with soda lime glass spheres with diameter of 337.5 micron (pore diameter 150 micron). The ratio between the average velocity of the RBCs and the average velocity of the carrying fluid (physiological saline) was close to 0.9. The RBCs migrated faster through the column than the carrying fluid mainly due to a hydrodynamic chr...
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