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BDNF-induced local protein synthesis and synaptic plasticity
Leal, Graciano; Comprido, Diogo; Duarte, Carlos B.Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission and longterm potentiation (LTP) in the hippocampus and in other brain regions, playing a role in the formation of certain forms of memory. The effects of BDNF in LTP are mediated by TrkB (tropomyosin-related kinase B) receptors, which are known to be coupled to the activation of the Ras/ERK, phosphatidylinositol 3-kinase...
Data: 2014
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Origem: Estudo Geral - Universidade de Coimbra
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