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p-Phenylenediamine sensitization is more prevalent in central and southern Euro...

Thyssen, JP; Andersen, KE; Bruze, M; Diepgen, T; Giménez-Arnau, AM; Gonçalo, Margarida; Goossens, A; Le Coz, C; McFadden, J; Rustemeyer, T; White, IR

BACKGROUND: Positive patch test reactions to p-phenylenediamine (PPD) are common. PPD is used in oxidative hair dyes and is also present in dark henna temporary 'tattoos'. Cross-sensitization to other contact allergens may occur. Because subjects sensitized to PPD are at risk of clinically severe reactions upon hair dyeing, there is a need for 'current' prevalence data on PPD sensitization. OBJECTIVES: To compa...


Hand eczema severity and quality of life: a cross-sectional, multicentre study ...

Agner, T; Andersen, KE; Brandão, FM; Bruynzeel, DP; Bruze, M; Frosch, P; Gonçalo, Margarida; Goossens, A; Le Coz, C; Rustemeyer, T; White, IR

BACKGROUND AND OBJECTIVES: Hand eczema is a chronic disease with negative impact on quality of life (QoL). In this study, QoL in hand eczema patients is assessed and related to age, sex, severity, and diagnostic subgroups. METHODS: A total of 416 patients with hand eczema from 10 European patch test clinics participated in the study. Data on QoL were obtained from a self-administered questionnaire using the Der...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia